Evidence map›Paper›PMID 41726763›Full record

ArticleNanotheranostics2026

Rapid method for the high purity isolation of bovine milk-derived extracellular vesicles via polyester (PET) capillary-channeled polymer (C-CP) fiber columns.

Carolina Mata, R Kenneth Marcus

Abstract read
In one paragraph

Article in Nanotheranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carolina MataDepartment of Chemistry, Biosystems Research Complex, Clemson University, Clemson, SC 29634-0973, USA.
R Kenneth MarcusDepartment of Chemistry, Biosystems Research Complex, Clemson University, Clemson, SC 29634-0973, USA.

Funding

Capillary-channeled polymers fibers and films - A platform technology for exosome isolation and analyticsR01GM141347 · NIGMS · CLEMSON UNIVERSITY · PI BRUCE, TERRI LANE FOSTER, MARCUS, RICHARD KENNETH · 2022 to 2025
$1.7M
JEOL 2100PLUS(CR)S10OD034282 · OD · UNIVERSITY OF GEORGIA · PI SALGUERO, TINA · 2023 to 2023
$1.2M
National Science Foundation CHE-2404088NIGMS NIH HHS R01 GM141347NIH HHS S10 OD034282
6 · The paper itself

Abstract

The use of raw bovine milk as a source of extracellular vesicles (EVs) has gained in interest for therapeutic applications due to its low cost, accessibility, low immunogenicity, and potential for oral delivery. To address the need to achieve higher throughput isolation of high-quality EVs, high performance liquid chromatography (HPLC) using a hydrophobic interaction chromatography (HIC) capture/elution program is performed on microbore, capillary-channeled polymer (C-CP) fiber columns.

Indexed as

Extracellular VesiclesMilkPolyestersAnimalsCattleChromatography, High Pressure LiquidHydrophobic and Hydrophilic InteractionsPolyestersbovine milk-derived extracellular vesicleshydrophobic interaction chromatographyPET C-CP fiber columnrapid EV isolation

Identifiers

PMID41726763
PMCPMC12923310

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.