Evidence map›Paper›PMID 41726640›Full record

ReviewACS omega2026

Monolithic Columns for the Isolation of Lectin: Principles, Advances and Prospects.

Ivonéa Soares do Nascimento, Charline Soares Dos Santos Rolim, Ana Cristina Freitas de Oliveira Meira, Jaime Vilela de Resende, Renata Cristina Ferreira Bonomo, Cristiane Martins Veloso, Rafael da Costa Ilhéu Fontan

Abstract readReview
In one paragraph

Review in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Organic polymer-based monoliths: structural design and integration into microreactors and flow analytical systems.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ivonéa Soares do NascimentoProcess Engineering Laboratory, Universidade Estadual do Sudoeste da Bahia, Itapetinga 45700-000, Brazil.
Charline Soares Dos Santos RolimProcess Engineering Laboratory, Universidade Estadual do Sudoeste da Bahia, Itapetinga 45700-000, Brazil.
Ana Cristina Freitas de Oliveira MeiraFood Refrigeration Laboratory, Department of Food Science, Universidade Federal de Lavras, Lavras 37200-900, Brazil.
Jaime Vilela de ResendeFood Refrigeration Laboratory, Department of Food Science, Universidade Federal de Lavras, Lavras 37200-900, Brazil.
Renata Cristina Ferreira BonomoProcess Engineering Laboratory, Universidade Estadual do Sudoeste da Bahia, Itapetinga 45700-000, Brazil.
Cristiane Martins VelosoProcess Engineering Laboratory, Universidade Estadual do Sudoeste da Bahia, Itapetinga 45700-000, Brazil.
Rafael da Costa Ilhéu FontanProcess Engineering Laboratory, Universidade Estadual do Sudoeste da Bahia, Itapetinga 45700-000, Brazil.ORCID https://orcid.org/0000-0001-9982-3418

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryogels are materials formed from the polymerization of monomers under freezing conditions and are mainly used as monolithic chromatography columns. Depending on the functionalization technique, they can be used for ion exchange chromatography, immobilized metal ion affinity chromatography (IMAC), hydrophobic interaction and more selective affinity methods. Due to their physical, chemical and hydrodynamic properties, cryogels find applications in various fields, such as the food industry for purification processes, the pharmaceutical, medical/biomedical and environmental industries, for the removal of waste or toxic substances from the environment. Affinity chromatography is a widely used method in liquid chromatography, and cryogels are closely related to it. Therefore, the aim here is to describe and analyze advances in the development of supermacroporous monolithic columns and their main applications focused on affinity chromatography. Thus, there is a vast field involving monolithic columns for application in affinity chromatography aimed at isolating biomolecules, including lectins. Lectins are glycoproteins with the ability to bind to carbohydrates and perform various functions such as antibacterial, antitumor, immunomodulatory and antiviral responses, among other applications. This review allows us to emphasize the great advances in the development and application of cryogels, materials that have wide applicability in various areas, such as food, biological, medical, biomedical, pharmaceutical and environmental. It is a product that is easy to synthesize and reproduce.

Identifiers

PMID41726640
PMCPMC12917641

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.