Evidence map›Paper›PMID 41726578›Full record

ArticlePediatric investigation2026

Interaction analysis of non-bacterial respiratory pathogens during and after the coronavirus disease 2019 pandemic in two cities along the eastern coast of China.

Wanxian Ye, Jishan Zheng, Yungang Yang, Xinyue Song, Xiang Yuan, Lan Yang, Jian Yu, Hailin Zhang, Shunhang Wen

Abstract read
In one paragraph

Article in Pediatric investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wanxian YeDepartment of Pediatric Respiratory Medicine National Key Clinical Specialty of Pediatric Respiratory Medicine Institute of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.
Jishan ZhengPediatric Respiratory Department Ningbo Women and Children's Hospital of Ningbo University Ningbo Zhejiang China.
Yungang YangDepartment of Pediatrics the First Affiliated Hospital of Xiamen University Xiamen Fujian China.
Xinyue SongDepartment of Pediatric Respiratory Medicine National Key Clinical Specialty of Pediatric Respiratory Medicine Institute of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.
Xiang YuanDepartment of Pediatric Respiratory Medicine National Key Clinical Specialty of Pediatric Respiratory Medicine Institute of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.
Lan YangDepartment of Pediatric Respiratory Medicine National Key Clinical Specialty of Pediatric Respiratory Medicine Institute of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.
Jian YuDepartment of Clinical Laboratory The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.
Hailin ZhangDepartment of Pediatric Respiratory Medicine National Key Clinical Specialty of Pediatric Respiratory Medicine Institute of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.
Shunhang WenDepartment of Pediatric Respiratory Medicine National Key Clinical Specialty of Pediatric Respiratory Medicine Institute of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China.ORCID https://orcid.org/0009-0000-9637-7053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: The coronavirus disease 2019 (COVID-19) pandemic and associated non-pharmaceutical interventions (NPIs) have significantly altered the epidemiology of respiratory pathogens. Understanding the interactions between non-bacterial respiratory pathogens is crucial for clinical management and surveillance. Objective: To investigate how interactions among non-bacterial respiratory pathogens in children changed during and after the COVID-19 pandemic in two cities in eastern China. Methods: This retrospective study reviewed the data of children hospitalized with acute respiratory tract infections in Wenzhou and Ningbo between March 1, 2021, and February 28, 2024. The SureX 13 respiratory pathogen multiplex kit was used to detect 13 pathogen types/subtypes in the respiratory tract secretion specimens. The chi-square test or Fisher's exact test, virus correlation, and vector autoregressive modelling were employed to evaluate correlations and dynamic changes in the weekly positive detection rates before and after the NPIs. Results: Among the 73 096 children tested, 65.18% had at least one non-bacterial respiratory pathogen, and 11.97% had multiple pathogens. Detection rates declined significantly by 56.65% during NPIs but rebounded by 75.46% afterward, particularly for Interpretation: The interactions between non-bacterial respiratory pathogens markedly changed after COVID-19, showing strengthened correlations, which were primarily negative in nature. These observations underscore the importance of the ongoing surveillance of respiratory pathogens in evolving NPIs and epidemiological patterns.

Indexed as

ChildrenCOVID‐19 pandemicNon‐bacterial respiratory pathogensPathogenVector autoregressive model

Identifiers

PMID41726578
PMCPMC12921633

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.