ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2024
Recruitment, Retention, and Participant Diversity in the Context of a Heart Failure Self-Care Digital Intervention Decentralized Clinical Trial.
Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
backgroundLow participant accrual is a persistent concern in physiological disease intervention trials, inflating costs and jeopardizing the timeliness and validity of findings. Investigators are increasingly adopting decentralized methods to facilitate participation.
objectiveTo add to the recruitment evidence base by describing the performance of direct and remote recruitment strategies in a decentralized randomized controlled trial of a digital intervention to improve heart failure self-care behaviors.
methodsWe conducted a descriptive analysis of referral, enrollment, and retention rates; cost; and sociodemographic diversity of participants across six recruitment streams. Data were collected from Sept 30, 2022 to June 30, 2025.
resultsDecentralized recruitment channels generated 97.5% of enrollments and achieved varying success with respect to sample representativeness. Enrollment rates progressed in accordance with proposed timelines. Retention at 6 months was 82.6%.
conclusionsDecentralized recruitment strategies are feasible, cost effective, and conducive to achieving enrollment targets.
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41726522PMC12919413What OpenQuestion holds
Registered trials
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