ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2024
Predicting Early-Onset Colorectal Cancer with Large Language Models.
Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
The incidence rate of early-onset colorectal cancer (EoCRC, age < 45) has increased every year, but this population is younger than the recommended age established by national guidelines for cancer screening. In this paper, we applied 10 different machine learning models to predict EoCRC, and compared their performance with advanced large language models (LLM), using patient conditions, lab results, and observations within 6 months of patient journey prior to the CRC diagnoses. We retrospectively identified 1,953 CRC patients from multiple health systems across the United States. The results demonstrated that the fine-tuned LLM achieved an average of 73% sensitivity and 91% specificity.
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41726501PMC12919599What OpenQuestion holds
Registered trials
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