Evidence map›Paper›PMID 41726356›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2026

Tele-Intensive Care Unit-associated Early Recognition of In-hospital Hemodynamic Events and Clinical Outcomes: A Multicenter Observational Study.

Moturu Dharanindra, Ramesh B Potineni, Supriya Rayana, Sravani Thommandru, Jahangeer Shaik, Karthikeya Jampala, Lakshmi Ssb Kakumanu, Sai T Uppalapati, Silpa C Nallapaneni, Vamsi K Madduri and 1 more

Abstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Author Response: From Tele-ICU "Alerts" to Tele-ICU "Assurance": Making Hemodynamic Surveillance Decision-grade and Globally Transferable.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  2. From Tele-ICU "Alerts" to Tele-ICU "Assurance": Making Hemodynamic Surveillance Decision-grade and Globally Transferable.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  3. Tele-ICU, Early Detection of Deterioration, and the Quest to Prevent In-hospital Cardiac Arrest.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Moturu DharanindraDepartment of Intensive Care Medicine, Westmead Hospital, University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-9446-5460
Ramesh B PotineniDepartment of Cardiology, Aster Ramesh Hospital, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0000-0001-6983-0828
Supriya RayanaDepartment of Pharmacy Practice, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0000-0001-9904-2574
Sravani ThommandruDepartment of Pharmacy Practice, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0002-3510-9447
Jahangeer ShaikDepartment of Information Technology (IT), Aster Ramesh Hospital, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0009-0003-3345-8827
Karthikeya JampalaDepartment of Anaesthesiology and Intensive Care, Aster Ramesh Hospital, Vijayawada, Andhra Pradesh, India.ORCID https://orcid.org/0009-0003-8519-259X
Lakshmi Ssb KakumanuDepartment of Pharmacy Practice, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0005-9752-3207
Sai T UppalapatiDepartment of Pharmacy Practice, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0004-0286-3384
Silpa C NallapaneniDepartment of Critical Care Medicine, Aster Ramesh Hospital, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0009-8018-536X
Vamsi K MadduriDepartment of Anaesthesia, Aster Ramesh Hospital, Ongole, Andhra Pradesh, India.ORCID https://orcid.org/0009-0005-4890-1785
Karthik C YalavarthiDepartment of Anaesthesia, Aster Ramesh Hospital, Guntur, Andhra Pradesh, India.ORCID https://orcid.org/0009-0007-6639-9252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: In-hospital cardiac arrest (IHCA) remains a major cause of mortality among hospitalized patients globally. This prospective, multicenter, observational study assessed the associations of a tele-intensive care unit (Tele-ICU) hemodynamic surveillance program and clinical outcomes in adult inpatients monitored across three tertiary-care hospitals in India. Patients and methods: From September 2024 to August 2025, 5,253 adult inpatients in ICUs, general wards, and Emergency Departments (EDs) were continuously monitored by a centralized Tele-ICU hub. Pre-specified thresholds for hemodynamic parameters generated real-time alerts, which were verified and adjudicated by Tele-ICU intensivists according to a standardized protocol. Outcomes, interventions, and mortality were analyzed using full multivariable logistic regression, with clearly defined denominators and clustering by site to account for within-site addressed. Results: A total of 2,278 patients (43.3%) experienced clinically significant hemodynamic alerts. The system's alerting and verification protocol demonstrated a sensitivity of 79.2% and specificity of 80.1%, with consistent performance across sites and locations. Median acute physiology and chronic health evaluation (APACHE) II score was 16 [interquartile range (IQR) = 12-22]. Patients experiencing verified alerts had a mortality rate of 12% ( Conclusion and clinical significance: The early recognition and verification of hemodynamic alerts in Tele-ICU were associated with improved clinical outcomes and a lower risk-adjusted mortality. How to cite this article: Dharanindra M, Potineni RB, Rayana S, Thommandru S, Shaik J, Jampala K,

Indexed as

Early recognitionHemodynamic monitoringIn-hospital cardiac arrestMortalityMulticenter studyObservational studyTele-intensive care unit

Identifiers

PMID41726356
PMCPMC12920382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.