ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2026
Frailty in Critically Ill Cancer Patients in a Lower-middle Income Country-Prevalence, Risk Factors, and Impact on Acute Clinical Outcomes and Postdischarge Health-related Quality of Life: A Single Center Study.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Frailty or Vulnerability? Interpreting Clinical Frailty Scale Cutoffs in Critically Ill Cancer Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Author Response: Frailty or Vulnerability? Interpreting Clinical Frailty Scale Cutoffs in Critically Ill Cancer Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Understanding Outcomes in Onco-critical Care: The Role of Frailty and Organ Failure.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Background and aims: Frailty is a multifaceted condition characterized by diminished physiological reserves, reduced resilience, and heightened vulnerability to stressors. Its prevalence among critically ill patients, particularly those with cancer, poses unique challenges due to pre-existing impairments and comorbidities. This study aims to evaluate the prevalence of frailty in critically ill cancer patients, identify associated risk factors, and assess its impact on acute clinical outcomes and 90 days postdischarge health-related quality of life (HRQOL). Patients and methods: A prospective, single-center cohort study was conducted between October 2021 and September 2022, enrolling critically ill cancer patients admitted to the intensive care unit (ICU). Frailty was assessed using the clinical frailty scale (CFS) within 48 hours of ICU admission. Data on demographics, illness severity [acute physiology and chronic health evaluation II (APACHE II) score], nutritional status, and clinical outcomes were collected. Ninety days postdischarge HRQOL was evaluated using the EuroQol 5-dimension 5-level (EQ-5D-5L) questionnaire. Results: All 627 enrolled patients were identified as frail, with 79.7% categorized as having mild frailty. Age ( Conclusion: Frailty is highly prevalent among critically ill cancer patients. Increasing frailty adversely impacts clinical outcomes and postdischarge HRQOL. Tailored interventions are essential to address the complex needs of this vulnerable population. How to cite this article: Sundaramurthy SK, Murali Rajagopalan TS, Balakrishnan P, Ramakrishnan N, Dominic Savio R. Frailty in Critically Ill Cancer Patients in a Lower-middle Income Country-Prevalence, Risk Factors, and Impact on Acute Clinical Outcomes and Postdischarge Health-related Quality of Life: A Single Center Study. Indian J Crit Care Med 2026;30(1):19-26.
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