ArticleOpen medicine (Warsaw, Poland)2026
Prevalence and risk factors of deep vein thrombosis in elderly: a systematic review and meta-analysis.
Article in Open medicine (Warsaw, Poland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Deep vein thrombosis (DVT) demonstrated significant health risk in elderly populations, with numerous comorbidities and biomarkers affecting its incidence. This study evaluated the prevalence, potential allied risk factors for DVT in elderly. Methods: A literature search was conducted across PubMed, Science Direct, Cochrane Library, and Google Scholar. After excluding studies, 26 studies were comprised in the study. Data were collected for DVT prevalence and associated risk factors. Results: A total of 11,651 participants comprised from China, Japan, Germany, Saudi Arabia, and Thailand. The overall DVT prevalence was 17.10 %, with higher prevalence in females (67.08 %) than males (32.92 %). Age was significantly associated with increased DVT risk (OR=1.54, 95 % CI: 0.34-2.73, p<0.01). While DVT incidence was insignificantly higher among hypertensive and diabetic patients. Significant associations identified between DVT occurrence and malignancy (OR=1.36, 95 % CI: 1.02-1.83, p<0.04), as well as recent surgical history (OR=1.34, 95 % CI: 1.01-1.77, p<0.04). Elevated D-dimer were strongly linked to DVT risk (OR=1.13, 95 % CI: 1.08-1.17, p<0.001). Conclusions: This review suggested the significant impact of aging, malignancy, recent surgery, and elevated D-dimer levels on DVT risk in elderly and recommends the assessment of clinical signs, risk factors, and biomarkers in elderly individuals.
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