ArticleJournal of the Society for Cardiovascular Angiography & Interventions2026
Impact of Anticoagulation on Valve Hemodynamics Following Transcatheter Valve-In-Valve Implantation.
Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Background: Transcatheter aortic valve implantation (TAVI) for prosthetic valve dysfunction is frequently associated with suboptimal echocardiographic outcomes. The effect of anticoagulation on preserving valve function is not well understood. Methods: Patients who underwent the valve-in-valve TAVI for failed prosthetic aortic valves between 2015 and 2023 at a large academic medical center were retrospectively included. Data on anticoagulation use, along with clinical and echocardiographic outcomes, were collected. The end point of the study was the effect of anticoagulation use on the changes in mean gradient, peak velocity (V Results: One hundred thirteen patients (43 women) with a mean Society of Thoracic Surgeons score of 5.8 ± 5.5 were included in the study. Of these, 42% underwent valve fracture, and anticoagulation was used in 69.3% patients at discharge and 53.3% at 1-year follow-up. The mean gradient (β = 4.46, Conclusions: Anticoagulation postvalve-in-valve TAVI may lead to lower mean gradients and peak velocities at 1-year follow-up. More data are needed to understand its impact on nonflow-dependent indices and clinical outcomes.
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