Evidence map›Paper›PMID 41725924›Full record

ArticleFrontiers in cardiovascular medicine2026

Case Report: Contrast adenosine stress echocardiography revealing microvascular dysfunction in cardiac AL amyloidosis.

Yuqian Dai, Yan Deng, Ni Lin, Feifei Che, Chunmei Li, Lixue Yin

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yuqian DaiDepartment of Anatomical Sciences, School of Medicine, St. George's University, St. George's, Grenada.
Yan DengDepartment of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Provincial People's, Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Ni LinDepartment of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Provincial People's, Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Feifei CheDepartment of Hematology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Chunmei LiDepartment of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Provincial People's, Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lixue YinDepartment of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan Provincial People's, Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis (CA) is a rare but increasingly recognized cause of restrictive cardiomyopathy. Noninvasive assessment of coronary microvascular dysfunction in CA can facilitate earlier diagnosis and improve disease monitoring. We present a case of light-chain (AL) cardiac amyloidosis manifesting as exertional angina with non-obstructive epicardial coronary arteries, in which contrast adenosine stress echocardiography combined with Doppler-derived coronary flow velocity reserve (CFVR) measurement revealed impaired myocardial perfusion and reduced CFVR. The findings were consistent with cardiac magnetic resonance (CMR) and laboratory results, confirming the diagnosis of CA. This case demonstrates the clinical application of contrast adenosine stress echocardiography as a practical adjunct to advanced imaging modalities for evaluating microvascular dysfunction in CA.

Indexed as

cardiac amyloidosiscase reportcontrast stress echocardiographyinfiltrative cardiomyopathymultiple myeloma

Identifiers

PMID41725924
PMCPMC12916374

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