Evidence map›Paper›PMID 41725715›Full record

ArticleFrontiers in neurology

Dynamic trajectory of cerebral autoregulation recovery after carotid artery stenting in severe carotid stenosis.

Xiaojuan Wang, Bo Li, Rong Guo, Xuke Zhang, Mingrui Zhu, Jiaxin Liu, Xiangnan Li, Muhui Lin

Abstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xiaojuan WangDepartment of Neurology, Dalian Medical University, Dalian, China.
Bo LiDepartment of Neurology, Dalian Medical University, Dalian, China.
Rong GuoDepartment of Clinical Neurophysiology, The People's Hospital of Liaoning Province, Shenyang, China.
Xuke ZhangDepartment of Neurology, Bengbu Medical College, Anhui, China.
Mingrui ZhuDepartment of Neurology, The People's Hospital of Liaoning Province, Shenyang, China.
Jiaxin LiuDepartment of Clinical Neurophysiology, The People's Hospital of Liaoning Province, Shenyang, China.
Xiangnan LiDepartment of Clinical Neurophysiology, The People's Hospital of Liaoning Province, Shenyang, China.
Muhui LinDepartment of Neurology, The People's Hospital of Liaoning Province, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the temporal changes and recovery patterns of dynamic cerebral autoregulation (dCA) after carotid artery stenting (CAS) in patients with severe internal carotid artery stenosis. Methods: In this prospective study, 44 patients undergoing CAS (19 symptomatic and 25 asymptomatic) and 44 age-matched healthy controls were enrolled. Patients in the CAS group underwent dCA assessments at four time points: pre-CAS (baseline, within 24 h prior to surgery), postoperative day 1 (POD 1), postoperative day 3 (POD 3), and 1 month postoperatively (POM 1). dCA was quantified using transfer function analysis (TFA), including phase difference (PD) and gain, to evaluate dCA. Results: Pre-CAS, patients had bilateral dCA impairment, worse on the affected (stenotic) side (PD: affected side: 30.56 ± 19.87° vs. unaffected side: 43.29 ± 23.29°, Conclusion: Unilateral severe carotid stenosis impairs bilateral dCA, while CAS significantly restores cerebral autoregulation. Recovery is faster on the affected side, reaching the unaffected level within 1 day, and both hemispheres reach healthy control levels by day 3. Early CAS intervention can timely improve dCA regardless of symptom status.

Indexed as

carotid artery stentingdynamic cerebral autoregulationinternal carotid arterysurgerytime course

Identifiers

PMID41725715
PMCPMC12921408

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