A Journey Through Time - Study Protocol for a Randomized Controlled Trial Testing the Add-on Effects of Imagery Rescripting to Ongoing Cognitive Behavioural Therapy in Patients With Depressive Disorders.

Amelie Endres, Anja Schaich, Arnoud Arntz, Eva Fassbinder, Fritz Renner

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Article in Clinical psychology in Europe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Amelie EndresDepartment of Clinical Psychology and Psychotherapy, Institute of Psychology, University of Freiburg, Freiburg, Germany.ORCID https://orcid.org/0009-0009-1586-2686

Anja SchaichDepartment of Psychiatry and Psychotherapy, University of Lübeck, Lübeck, Germany.ORCID https://orcid.org/0000-0002-7398-8756

Arnoud ArntzDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-7992-2272

Eva FassbinderClinic for Psychiatry, University of Kiel, Kiel, Germany.ORCID https://orcid.org/0000-0003-3017-4514

Fritz RennerDepartment of Clinical Psychology and Psychotherapy, Institute of Psychology, University of Freiburg, Freiburg, Germany.ORCID https://orcid.org/0000-0002-1692-449X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with depression often report recurring memories of stressful events from the past (e.g. experiences of rejection, emotional or physical abuse). These distressing memories, commonly dating back to childhood, can contribute to the development and maintenance of depression through their impact on cognitive schemas. The method of Method: Sixty-six patients with MDD who are currently receiving treatment (CBT) will be randomized to either (1) the experimental condition (ImRs) or (2) the control condition (imagery relaxation). Reduction of depressive symptoms, measured by the Beck Depression Inventory (BDI-II) is the primary outcome. The BDI-II will be assessed at baseline, post-intervention, and at 4-week and 8-week follow-ups. Discussion: This study will help to clarify whether adding three ImRs sessions improves the effectiveness of CBT for depression. We outline the next steps for future research and highlight the potential of this novel intervention for depression.

Indexed as

distressing memoriesimagery rescriptingmajor depressive disorder (MDD)

Identifiers

PMID41725694

DOI10.32872/cpe.16709

PMCPMC12923180

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.