Evidence map›Paper›PMID 41725598›Full record

ArticleDevelopmental medicine and child neurology2026

Developmental stuttering with common and complex phenotypes.

Sarah E Horton, Daisy A Shepherd, Stephanie Siemers, Miya St John, Juliette Catherall, Ingrid E Scheffer, Angela T Morgan

Abstract read
In one paragraph

Article in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sarah E HortonMurdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0003-0831-9705
Daisy A ShepherdMurdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0001-8540-0473
Stephanie SiemersMurdoch Children's Research Institute, Parkville, Victoria, Australia.
Miya St JohnMurdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0003-4723-937X
Juliette CatherallMurdoch Children's Research Institute, Parkville, Victoria, Australia.
Ingrid E SchefferMurdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0002-2311-2174
Angela T MorganMurdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0003-1147-7405

Funding

Centre for Research Excellence in Speech and Language Neurobiology (CRE-SLANG) 1116976National Health and Medical Research Council 1105008National Health and Medical Research Council 1195955
6 · The paper itself

Abstract

aimTo describe the phenotypic spectrum associated with stuttering.

methodIndividuals with current or resolved developmental stuttering self-referred. Surveys assessed stuttering characteristics (onset, negative impact, family history) and health (early development, other conditions). Speech and non-verbal intelligence were assessed using conversation and the Wechsler standardized scales. Sample sizes varied across assessments (n = 266-327). Latent class analysis identified unobserved groups based on assessment data.

resultsA total of 327 participants (231 male, 71%) with a median age of 57 years (range: 5-90 years) were recruited, 282 of 296 (95%) with current stuttering and 14 of 296 (5%) with resolved stuttering. Onset was 4 years or younger for 187 of 322 (58%) participants; 207 of 325 (64%) had a positive family history of stuttering, 58 of 325 (18%) had developmental delay, and 38 of 264 (14%) had below average non-verbal intelligence. Common co-occurring conditions included sleep, hearing, vision, and immune conditions, migraine, anxiety, and depression. Analysis revealed two groups: 295 of 327 (90%) participants had the common phenotype and 32 of 327 (10%) had a complex phenotype, with more severe stuttering, greater negative impact of stuttering, more frequent anxiety, lower non-verbal intelligence, and neurodevelopmental disorders.

interpretationPhenotypic analysis of a large cohort of who stutter identified 90% with a common phenotype and 10% with a complex phenotype. Both had co-occurring disorders requiring multidisciplinary support.

Indexed as

Developmental DisabilitiesStutteringAdolescentAdultAgedAged, 80 and overChildChild, PreschoolComorbidityFemaleHumansIntelligenceMaleMiddle AgedPhenotypeYoung Adult

Identifiers

PMID41725598
PMCPMC13545487

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.