Observational studyStroke2026
Adherence to Different Dietary Patterns and Subsequent Risk of Total, Ischemic, and Hemorrhagic Stroke.
Observational study in Stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
backgroundAdherence to healthy dietary patterns has been related to lower cardiovascular disease risk. However, few studies have examined prospective associations between adherence to different healthy dietary scores and the incidence of stroke and its subtypes. The aim of this study was to prospectively examine the associations between adherence to 4 recognized healthy dietary patterns and the risk of total and ischemic stroke in an existing dietary-based randomized controlled trial.
methodsThis is a secondary observational cohort analysis of 7447 participants at high cardiovascular disease risk enrolled in the PREDIMED trial (Prevención Con Dieta Mediterranea). Dietary scores for 4 healthy dietary patterns, including the Mediterranean, Dietary Approaches to Stop Hypertension (DASH), Mediterranean-DASH Diet Intervention for Neurodegenerative Delay diets, and the Planetary Health Diet Index, were derived from repeated food frequency questionnaires. Participants were classified into quintiles of cumulative average adherence of the 4 dietary scores. Multivariable-adjusted Cox proportional hazards models were used to estimate hazard ratios and 95% CIs for associations with the healthy dietary scores and risk of stroke and stroke subtypes.
resultsDuring a total of 31 024 person-years of follow-up (median, 4.3 years), 135 stroke cases were documented (112 ischemic and 23 hemorrhagic strokes). Comparing the highest versus the lowest quintile of dietary scores, the multivariable-adjusted hazard ratio of total stroke was 0.26 (95% CI, 0.14-0.51) for Mediterranean diet and 0.25 (95% CI, 0.13-0.51) for Mediterranean-DASH Diet Intervention for Neurodegenerative Delay diet, while no significant associations were observed for the DASH diet (adjusted hazard ratio, 0.76 [95% CI, 0.42-1.39]) or the Planetary Health Diet Index (adjusted hazard ratio, 0.57 [95% CI, 0.30-1.08]). Similar associations were observed for ischemic stroke.
conclusionsIn individuals at high cardiovascular disease risk, greater adherence to the Mediterranean and Mediterranean-DASH Diet Intervention for Neurodegenerative Delay diets was associated with a lower risk of total stroke and ischemic stroke. REGISTRATION: URL: https://www.isrctn.com/; Unique identifier: ISRCTN35739639.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.