Evidence map›Paper›PMID 41725118›Full record

ArticleVeterinary surgery : VS2026

Serial postoperative peritoneal fluid analyses in horses with naturally-occurring strangulating and non-strangulating gastrointestinal lesions.

Maria E Granello, Jenna M Young, Dana B Cleff, Emma B M Banks, Troy N Trumble

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Article in Veterinary surgery : VS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Maria E GranelloDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.ORCID https://orcid.org/0000-0001-9169-6565
Jenna M YoungDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.ORCID https://orcid.org/0000-0002-5419-9938
Dana B CleffDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Emma B M BanksDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.
Troy N TrumbleDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA.ORCID https://orcid.org/0000-0001-6105-8052

Funding

American College of Veterinary Surgeons Foundation 6259College of Veterinary Medicine, University of Minnesota
6 · The paper itself

Abstract

objectiveTo describe characteristics of postoperative peritoneal fluid following exploratory laparotomy for naturally-occurring gastrointestinal lesions in horses. STUDY

designProspective, observational cohort study. ANIMALS: A total of 26 client-owned horses that underwent exploratory laparotomy for naturally-occurring gastrointestinal lesions.

methodsAbdominocentesis was performed pre- or intraoperatively, and at three time points postoperatively (24, 72, and 168 h). Peritoneal lactate, total protein (TP), total nucleated cell count (TNCC), cytology, and systemic lactate were performed at each time point, if possible. To account for repeated measures, a linear mixed model analysis was performed for each dependent variable listed above.

resultsHorses were divided into groups based on the gastrointestinal lesion diagnosed at surgery (14 strangulating and 12 non-strangulating). Peritoneal lactate (p < .001) and TP (p = .02) were significantly higher preoperatively in horses with strangulating compared to non-strangulating lesions, with no significant differences between lesion groups for any postoperative measurement. Peritoneal lactate and TP concentrations remained above normal for the entire postoperative study period in both groups. Systemic lactate returned to normal concentrations by 24 h postoperatively with both groups being significantly lower than preoperative concentrations (p = .02). Peritoneal TNCC concentrations increased in strangulating (p = .001) and non-strangulating (p < .001) horses at 24 h postoperatively compared to preoperatively.

conclusionRegardless of lesion, peritoneal fluid lactate and TP remained above normal at 1 week following exploratory laparotomy for naturally-occurring gastrointestinal lesions in horses. CLINICAL SIGNIFICANCE: Current reference values for preoperative fluid sample analyses should not be used in the postoperative period.

Indexed as

Ascitic FluidGastrointestinal DiseasesHorse DiseasesAnimalsFemaleHorsesLactic AcidLaparotomyMalePostoperative PeriodProspective StudiesLactic Acid

Identifiers

PMID41725118
PMCPMC13069231

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