Evidence map›Paper›PMID 41725029›Full record

ArticleJournal of cosmetic dermatology2026

Punch Excision Combined With Radiotherapy for Keloid Treatment.

Yunfeng Guan, Meiling Huang

Abstract readComparative Study
In one paragraph

Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yunfeng GuanHuzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, China.
Meiling HuangHuzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPunch excision is gaining recognition in keloid management. Its distinct mechanism from conventional surgery necessitates a re-evaluation of the efficacy and safety when combined with radiotherapy (RT), an area currently lacking evidence.

aimsTo investigate the clinical efficacy and safety of punch excision combined with RT for treating trunk keloids and to compare the differences between perioperative (RT initiated one day before surgery) and postoperative RT (RT within 24 h after surgery) regimens.

methodsA retrospective study was conducted on patients with trunk keloids treated with punch excision combined with electron beam RT from January 2022 to January 2024. Outcomes were assessed using the Patient and Observer Scar Assessment Scale (POSAS) and records of adverse reactions.

resultsThe study included 34 patients. At 18 months, all keloids improved significantly without recurrence. The total Observer Scale score decreased by 52.73% and the Patient Scale score by 62.77%. No significant difference in POSAS scores was found between the two groups at 18 months. The perioperative group showed advantages in shorter postoperative bleeding duration and lower incidence of moderate-to-severe acute pain.

conclusionPunch excision combined with RT is effective for trunk keloids. While long-term cosmetic outcomes are similar between perioperative and postoperative RT, the perioperative regimen offers benefits in reducing early postoperative complications.

Indexed as

Dermatologic Surgical ProceduresKeloidAdolescentAdultCombined Modality TherapyFemaleHumansMaleMiddle AgedPostoperative HemorrhagePostoperative PainRadiotherapy, AdjuvantRetrospective StudiesTorsoTreatment OutcomeYoung Adultadverse effectskeloidpunch excisionradiotherapytreatment outcome

Identifiers

PMID41725029
PMCPMC12926515

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.