Evidence map›Paper›PMID 41725005›Full record

ArticleJournal of orthopaedic surgery and research2026

Regional oximetry for diagnosing compartment syndrome: a scoping review.

Linda Yuhan Tang, Dave Osinachukwu Duru, Andrew Browne, Andrew Kailin Zhou, Saroop Nandra, Matija Krkovic

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedic surgery and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Linda Yuhan TangSchool of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, UK. lint7764@gmail.com.ORCID http://orcid.org/0009-0002-0395-3408
Dave Osinachukwu DuruSchool of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, UK.ORCID http://orcid.org/0009-0005-8396-6146
Andrew BrowneNuffiled Department of Population Health, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-4215-7842
Andrew Kailin ZhouUniversity of Warwick, Warwick, UK.ORCID http://orcid.org/0000-0001-6656-8123
Saroop NandraTrauma and Orthopaedics Department, University Hospital Coventry and Warwickshire, Coventry, UK.
Matija KrkovicDepartment of Trauma and Orthopaedics, Addenbrookes Major Trauma Unit, Cambridge University Hospitals, Cambridge, UK.ORCID http://orcid.org/0000-0003-2172-2849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiagnosis of compartment syndrome remains challenging, as intracompartmental pressure (ICP) monitoring measures mechanical pressure rather than tissue perfusion. Near-infrared spectroscopy (NIRS) enables non-invasive, continuous assessment of tissue oxygen saturation (StO

methodsFollowing PRISMA-ScR guidelines, PubMed, EMBASE, Cochrane Library, ClinicalTrials.gov, and WHO-ICTRP were searched to April 2025 for studies evaluating NIRS in acute (ACS) or chronic exertional (CECS) compartment syndrome. Data on diagnostic accuracy, device protocols, and patient characteristics were extracted. Studies reporting comparable StO

resultsTwenty-three studies (n = 1000) were included. In ACS, some demonstrated strong correlation with perfusion pressure and post-fasciotomy StO

conclusionNIRS provides a physiologically relevant but technically variable indicator of compartmental perfusion, which may complement, but not replace, ICP monitoring for compartment syndrome. The results presented are hypothesis-generating and require prospective trials with standardised protocols, inclusive calibration, and prospective validation before clinical adoption of NIRS.

Indexed as

Compartment SyndromesOximetryOxygen SaturationHumansOxygenSpectroscopy, Near-InfraredOxygenCompartment syndromeIntracompartmental pressureIschemia monitoringNear-infrared spectroscopyNon-invasive diagnosticsRegional oximetry

Identifiers

PMID41725005
PMCPMC13037034

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