ReviewJournal of cannabis research2026
Cannabis: from crop to shop-some insights about stability to access quality control.
Review in Journal of cannabis research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCannabis sativa L. is increasingly used for medicinal and commercial purposes, yet most reviews treat chemical composition, ecology, and post-harvest processing as separate topics. This manuscript advances a conceptual framework that links chemical stability, chemodiversity, and post-harvest quality across the production chain (“crop to shop”), emphasizing and detailing how environmental and technological drivers shape cannabinoid and terpenoid profiles and, ultimately, product standardization.
methodsWe conducted a structured scoping review with bibliometric mapping of studies on volatile oils from inflorescences (1963–2025), applying explicit eligibility criteria and extracting metadata on genotype, collection site, plant state, extraction procedure, and analytical platforms. To synthesize chemical patterns, we employed exploratory chemometric summaries (principal component analysis and hierarchical grouping) and comparative narrative analyses of pre- and post-harvest factors (e.g., drying, grinding, extraction, storage, and others), and their implications for stability and quality assessment.
resultsAcross regions, chemical stability emerged as the central axis organizing chemodiversity, ecological roles, and quality outcomes. Pre-harvest conditions (cultivar, environment, phenology, and others) and post-harvest practices (drying regimes, particle size, extraction choices, storage conditions such as temperature, light, oxygen, and moisture) consistently redirected volatile and non-volatile profiles, with predictable formation or loss of key markers. The mapping highlights geographic concentration of research in Europe, the underrepresentation of the Americas, Oceania, and Africa, and limited coverage of minor cannabinoids and oxygenated terpenoids despite their technological relevance. The synthesis clarifies when technological steps favor sesquiterpenes versus monoterpenes, how trichome integrity protects active compounds, and why water activity and packaging permeability are decisive for stability. This review also identifies operational gaps regarding winterization parameters, sterilization impacts, and the scale-up of greener extraction methods.
conclusionsBy integrating phytochemistry, chemical ecology, and stability science, this review proposes a stability–chemodiversity–quality framework that distinguishes this approach from prior reviews. The framework supports actionable guidelines for cultivation choices, post-harvest handling, extraction designs, packaging, and storage to improve reproducibility and labeling accuracy. It also sets priorities for future research: standardized stability testing across matrices, inclusion of minor constituents, ecologically informed phenology, and validation of processing models based on moisture dynamics and oxygen control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.