Evidence map›Paper›PMID 41724763›Full record

ArticleNature communications2026

Subtypes of adolescent major depressive disorder characterized by divergent information dynamics in sensory-association cortices.

Xiaobo Liu, Bin Wan, Xinyu Wu, Xihan Zhang, Lang Liu, Siyu Long, Ruiyang Ge, Ruifang Cui, Xin Wen, Xiaoqiang Liu and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaobo Liu *Department of Psychiatry, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan University of Science and Technology, Wuhan, China.
Bin Wan *Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Xinyu WuSchool of Interdisciplinary Science, Beijing Institute of Technology, Beijing, China.ORCID http://orcid.org/0009-0003-6930-3042
Xihan ZhangDepartment of Psychology, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-2630-0063
Lang LiuDepartment of Human Genetics, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0002-0348-2258
Siyu LongMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.
Ruiyang GeDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
Ruifang CuiSchool of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Xin WenSchool of Software, Taiyuan University of Technology, Taiyuan, China.
Xiaoqiang LiuFirst Quanzhou Hospital Affiliated to Fujian Medical University, Quanzhou, China.
Wei PengDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-2892-5764
Guoyuan YangSchool of Interdisciplinary Science, Beijing Institute of Technology, Beijing, China. yanggy@bit.edu.cn.ORCID http://orcid.org/0000-0002-7864-3714
Yujun GaoDepartment of Psychiatry, Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan University of Science and Technology, Wuhan, China. 2021103020031@whu.edu.cn.ORCID http://orcid.org/0000-0002-6762-5131

Funding

National Natural Science Foundation of China (National Science Foundation of China) 62336002National Natural Science Foundation of China (National Science Foundation of China) 82302175
6 · The paper itself

Abstract

Adolescent major depressive disorder (MDD) involves complex and heterogeneous alterations in brain functional organization. A possible explanation is the disruption of individualized brain maturation during adolescence, which typically transitions from lower-order sensory to higher-order association regions. To test this hypothesis, we analyzed resting-state functional MRI data using advanced matrix decomposition techniques to extract organizational gradients, temporal dynamics, and information flow. Clustering sensory-association gradient features in our main sample (N

Indexed as

Major Depressive DisorderAdolescentBrain MappingChildFemaleHumansMagnetic Resonance ImagingMale

Identifiers

PMID41724763
PMCPMC13039935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.