Evidence map›Paper›PMID 41724736›Full record

ArticleObesity (Silver Spring, Md.)2026

Diagnostic Performance of BMI and Waist Circumference in Detecting Excess Adiposity.

John C Lin, Clara E Tandar, Simar S Bajaj, Fatima C Stanford

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John C LinPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Clara E TandarWarren Alpert Medical School, Brown University, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0001-5382-3500
Simar S BajajStanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-8498-9674
Fatima C StanfordNeuroendocrine Unit, Nutrition Obesity Research Center (NORCH), MGH Weight Center, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-4616-533X

Funding

Creating Opportunities for Unparalleled Researchers to Achieve Growth and Excellence (COURAGE)U24DK132733 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MORONE, NATALIA E., STANFORD, FATIMA CODY · 2022 to 2025
$3.3M
Accelerating Research Advancement for Investigators Underrepresented in AcademiaUE5DK137285 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Fatima Cody Stanford, Takara Leah Stanley · 2023 to 2026
$621k
NIH HHS NIDDK P30 DK040561NIH HHS U24 DK132733NIH HHS UE5 DK137285
6 · The paper itself

Abstract

objectiveThis study compared the diagnostic performance of BMI, waist circumference (WC), and Lancet Commission (LC) criteria for assessing excess adiposity measured by dual-energy X-ray absorptiometry (DEXA) in US adults.

methodsUsing 2011-2018 NHANES data, we included 10,747 adults aged 20-59 years with relevant data. We evaluated the diagnostic performance (sensitivity, specificity, positive and negative predictive values [PPV, NPV], area under the curve [AUC]) of BMI thresholds, waist-based measures, and LC criteria for excess adiposity, as defined by DEXA.

resultsThe weighted prevalence of DEXA-defined excess adiposity was 36.4%. CDC BMI thresholds demonstrated 74.6% sensitivity and 82.2% specificity (PPV, 67.0%; NPV, 87.0%). Waist-based measures showed higher sensitivity and lower specificity than BMI; NHLBI WC thresholds produced 88.5% sensitivity and 66.7% specificity. LC criteria performed variably: BMI plus ≥ 1 waist measure had 74.6% sensitivity and 82.2% specificity, whereas ≥ 2 waist measures had 88.5% sensitivity and 66.8% specificity. The AUC values were 0.876 for BMI, 0.882 for WC, 0.887 for waist to height ratio, and 0.715 for waist to hip ratio.

conclusionsWaist-based definitions were more sensitive than BMI, whereas BMI provided greater specificity. LC criteria performed comparably to existing definitions. Incorporating WC into screening may improve the detection of excess adiposity.

Indexed as

AdiposityBody Mass IndexObesityWaist CircumferenceAbsorptiometry, PhotonAdultFemaleHumansMaleMiddle AgedNutrition SurveysSensitivity and SpecificityUnited StatesYoung Adult

Identifiers

PMID41724736
PMCPMC13032046

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.