Evidence map›Paper›PMID 41724670›Full record

ReviewMicrobiologyOpen2026

Research Progress in the Treatment of Vaginitis With Bioactive Compounds: Targeting of Vaginal Microflora.

Yongming Li, Huiyu Liu, Ruihan Li, Rong Li, Jiaqi Liu

Abstract readReview
In one paragraph

Review in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yongming LiDepartment of Gynecology, Guigang Maternal and Child Health Care Hospital, Guigang, China.
Huiyu LiuCollege of Pharmacy, Guangxi Medical University, Nanning, China.
Ruihan LiEducation Department of Guangxi Zhuang Autonomous Region, Key Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China.
Rong LiEducation Department of Guangxi Zhuang Autonomous Region, Key Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China.ORCID 0000-0002-8210-1213
Jiaqi LiuEducation Department of Guangxi Zhuang Autonomous Region, Key Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaginitis, a common gynecological ailment among women, poses a considerable health challenge with high recurrence rates even after conventional treatment. Vaginitis includes more common forms, such as bacterial vaginosis, vulvovaginal candidiasis, and Trichomonas vaginalis (TV), and less common forms, including senile vaginitis, infantile vaginitis, viral vaginitis, and mixed vaginitis. Conventional treatment approaches for vaginitis involve medications, such as metronidazole and clindamycin; however, long-term use of these agents raises concerns about adverse reactions, disruption of the vaginal ecosystem, and antibiotic resistance. Bioactive compounds from Traditional Chinese Medicine (TCM), known for their lower toxicity and multifaceted biological activity, are effective for treating vaginitis with fewer side effects and a focus on restoring a healthy vaginal microecology. TCM decoctions exhibit internal effectiveness, while local TCM treatments utilize external medications and modalities, such as irrigation and fumigation sitz baths. This review offers insights to guide vaginitis treatment and provides a theoretical foundation for the development and application of herbal therapies for vaginitis.

Indexed as

Drugs, Chinese HerbalVaginaVaginitisCandidiasis, VulvovaginalFemaleHumansMedicine, Chinese TraditionalTrichomonas VaginitisVaginosis, BacterialDrugs, Chinese Herbalbioactive compoundsmicroflorapharmacological activitiesvaginitis

Identifiers

PMID41724670
PMCPMC12928029

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.