ArticleMovement disorders clinical practice2026
Subthalamic Nucleus Deep Brain Stimulation Improves Kinetic Tremor in Parkinson's Disease.
Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough resting tremor is a characteristic feature of Parkinson's disease (PD), many patients also suffer from action tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in reducing motor symptoms. However, it is unclear to what extent STN-DBS improves action tremor in PD, particularly kinetic tremor.
objectivesEvaluate the effectiveness of STN-DBS on resting, postural, and kinetic tremor, with particular focus on kinetic tremor.
methodsPD patients treated with bilateral STN-DBS were included. Patients with a score of ≥1 for tremor subtypes in either stimulation condition were included for tremor subtype analyses. The Movement Disorders Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) was administered OFF-medication, for both the OFF- and ON-stimulation condition, 6-12 months post-surgery. Wilcoxon signed-rank tests were used and effect sizes calculated. In addition, sensitivity analyses and a systematic literature review was performed.
results422 patients were included. For tremor subtype analyses, 251 patients were included for resting tremor amplitude, 270 for resting tremor constancy, 215 for postural tremor and 144 for kinetic tremor. DBS significantly improved all tremor subtypes (P < 0.001). Effect sizes were very large across tremor subtypes (Cohen's d > 1.00). Mean percentage improvement was comparable among resting (71.3%), postural (64.6%), and kinetic (65.1%) tremor. Similarly, the proportion of patients experiencing complete bilateral tremor resolution was consistent across tremor subtypes, 50.2% for resting, 55.8% for postural, and 51.4% for kinetic tremor.
conclusionsBilateral STN-DBS appears to improve all tremor subtypes in PD equally, including postural and kinetic tremor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.