Evidence map›Paper›PMID 41724205›Full record

ArticleACR open rheumatology2026

Rheumatoid Arthritis Diagnostic and Monitoring Testing Patterns by Physicians and Advanced Practice Providers in the United States, 2012 to 2024.

Min Kyung Lee, Karis Lee, David Alfego, Stanley J Naides

Abstract read
In one paragraph

Article in ACR open rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Min Kyung LeeLabcorp, Burlington, North Carolina.ORCID https://orcid.org/0000-0001-9558-4819
Karis LeeLabcorp, Burlington, North Carolina.ORCID https://orcid.org/0009-0008-1447-3956
David AlfegoLabcorp, Burlington, North Carolina.ORCID https://orcid.org/0000-0002-0465-9131
Stanley J NaidesLabcorp, Burlington, North Carolina.ORCID https://orcid.org/0000-0001-9339-7104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate longitudinal trends in rheumatoid arthritis (RA) diagnosis and monitoring by physicians and advanced practice providers (APPs) as measured by laboratory testing.

methodsWe conducted a retrospective review of RA-associated diagnostic and monitoring tests ordered through Labcorp by 7,026 physicians and 2,188 APPs in primary care and rheumatology between 2012 and 2024. Diagnostic tests include conventional markers (rheumatoid factor and anti-cyclic citrullinated peptide) and emerging markers (14.3.3 eta protein, anti-citrullinated α-enolase peptide 1, anti-carbamylated protein, and anti-citrullinated vimentin antibodies). Panel tests combine these markers to enhance diagnostic accuracy. Monitoring tests include the Vectra tests.

resultsFrom 2012 to 2024, rheumatology APPs who consistently ordered RA-associated tests annually through Labcorp increased by 411.8%, whereas rheumatology physicians who consistently ordered RA-associated tests through Labcorp grew by 58.5%. Compared with rheumatology physicians, rheumatology APPs ordered 37.9 fewer conventional markers (P = 2.7 × 10

conclusionWe observed a rise in APP contributions to RA-diagnostic and RA-monitoring test ordering, consistent with their growing presence within the rheumatology workforce.

Identifiers

PMID41724205
PMCPMC12927980

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