Evidence map›Paper›PMID 41723813›Full record

ArticleJournal of analytical toxicology2026

Simultaneous analysis of Δ9-THC, Δ8-THC, CBD, and CBN in breath aerosols collected using cannabix technologies breath collection unit.

Shaza Deeb, Zaire E Fabian, Mikko Määttä, Pedro Fraccarolli, David A Engelhart

Abstract read
In one paragraph

Article in Journal of analytical toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shaza DeebOmega Laboratories, Inc., Mogadore, OH 44260, United States.ORCID 0009-0000-6160-7146
Zaire E FabianOmega Laboratories, Inc., Mogadore, OH 44260, United States.
Mikko MäättäCannabix Technologies Inc., Burnaby, BC V5A 4R4, Canada.
Pedro FraccarolliCannabix Technologies Inc., Burnaby, BC V5A 4R4, Canada.
David A EngelhartOmega Laboratories, Inc., Mogadore, OH 44260, United States.

Funding

Omega Laboratories, Mogadore, OH, USA and Cannabix Technologies Inc., Burnaby, BC, Canada
6 · The paper itself

Abstract

A simple, accurate, and cost-effective liquid chromatography-tandem mass spectrometric (LC-MS/MS) method has been developed and validated for the simultaneous quantification of Δ9-tetrahydrocannabinol (Δ9-THC), Δ8-tetrahydrocannabinol (Δ8-THC), cannabidiol (CBD), and cannabinol (CBN) in breath aerosols collected using the Cannabix Technologies' Breath Collection Unit (BCU). The method is suitable for use in workplace drug testing and in the investigation of driving under the influence of drugs (DUID) cases. The method was validated according to ANSI/ASB Standard 036, First Edition 2019 guidelines. A lower limit of quantification (LLOQ) of 2.5 pg/L was achieved. Calibration curves were linear (R2 > 0.995) and quality control (QC) accuracy between 91.3% and 100.5% with precision (%CV) less than 17.7%. No major matrix effects or drug interferences were observed. Samples were stable at room temperature and refrigerated at 2-8°C up to 7 days. Breath samples were collected using the BCU from volunteer regular cannabis users before cannabis consumption and at multiple timepoints after smoking cannabis up to 90 minutes. The results verified the methods ability to capture and quantitate the cannabinoids in breath. The data indicated similar concentration versus time trends for THC metabolism assessed from breath to that previously reported from blood. Breath is an alternative, non-invasive sample matrix that holds promise for identifying recent cannabis use.

Indexed as

CannabidiolCannabinoidsCannabinolDronabinolSubstance Abuse DetectionAerosolsBreath TestsChromatography, LiquidHumansLimit of DetectionLiquid Chromatography-Mass SpectrometryReproducibility of ResultsTandem Mass SpectrometryAerosolsCannabidiolCannabinoidsCannabinolDronabinol

Identifiers

PMID41723813
PMCPMC13218819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.