Evidence map›Paper›PMID 41723767›Full record

ArticleTransgenic research2026

Boosting β-carotene in rice and wheat grains through seed-specific expression of a modified wheat or gene.

Parul Sirohi, Ritika Vishnoi, Suchi Baliyan, Bidya Bhushan Gupta, Pratibha Demiwal, Hugo Germain, Debabrata Sircar, Harsh Chauhan

Abstract read
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In one paragraph

Article in Transgenic research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Parul SirohiDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India.
Ritika VishnoiDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India.
Suchi BaliyanDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India.
Bidya Bhushan GuptaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India.
Pratibha DemiwalDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India.
Hugo GermainDepartment of Chemistry, Biochemistry and Physics, University of Quebec Trois Rivieres, Trois-Rivières, QC, Canada.
Debabrata SircarDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India.
Harsh ChauhanDepartment of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, India. harsh.chauhan@bt.iitr.ac.in.ORCID 0000-0002-1396-5464

Funding

Indian Institute of Technology Roorkee FIG-100677
6 · The paper itself

Abstract

Vitamin A deficiency is a major public health problem affecting up to 50% of the world's population, as staple food crops like wheat and rice, which are often poor in many essential micronutrients such as vitamin A, are major staple food crops. Biofortification of cereal crops with β-carotene (provitamin A) through genetic engineering is a potential solution to overcome vitamin A deficiency. The Orange (Or) protein is involved in the regulation of carotenoid accumulation and previous studies demonstrated high carotenoid accumulation due to a single-nucleotide polymorphism (SNP) in the CDS leading to substitution of Arg to His in the OR protein results in carotenoid accumulation. In the present study, we showed that this substitution of a single amino acid at position 110 (Arg to His) of wild-type wheat TaOr (referred to as TaOr

Indexed as

beta CaroteneOryzaPlant ProteinsPlants, Genetically ModifiedSeedsTriticumCarotenoidsEdible GrainGene Expression Regulation, PlantPolymorphism, Single NucleotidePromoter Regions, Geneticbeta CaroteneCarotenoidsPlant ProteinsCerealsHidden hungerPro-vitaminsSingle nucleotide polymorphism

Identifiers

PMID41723767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.