Evidence map›Paper›PMID 41723542›Full record

ArticleBMC research notes2026

Perspectives from Sri Lankan physicians on current approaches to diagnosing and managing lower respiratory tract infections.

Dhammika R Palangasinghe, U H B Y Dilshan, Warsha D De Zoysa, Jayani Gamage, Maria D Iglesias-Ussel, Champica K Bodinayake, Ajith De S Nagahawatte, W M D Gaya B Wijayaratne, Stefany Olague, M R P Kurukulasooriya and 14 more

Abstract read
In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Dhammika R Palangasinghe *Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka. drpalangasinghe1984@gmail.com.
U H B Y Dilshan *Duke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka. dilshan.yaz@gmail.com.
Warsha D De ZoysaDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Jayani GamageDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Maria D Iglesias-UsselDepartment of Medicine, School of Medicine, Duke University, Durham, NC, 27708, USA.
Champica K BodinayakeDepartment of Medicine, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Ajith De S NagahawatteDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
W M D Gaya B WijayaratneDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Stefany OlagueDuke Clinical Research Institute, Duke University, Durham, NC, 27708, USA.
M R P KurukulasooriyaDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Senali A WeerasingheDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
M H M PremamaliDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
James S NgochoDepartment of Epidemiology and Applied Biostatistics, KCMC University, 25101, Moshi, Tanzania.
Armstrong ObaleDuke-Ruhuna Collaborative Research Centre, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Hrishikesh ChakrabortyDuke Clinical Research Institute, Duke University, Durham, NC, 27708, USA.
Truls ØstbyeDepartment of Family Medicine and Community Health, Duke University, Durham, NC, 27708, USA.
Avi KennyDuke Global Health Institute, Duke University, Durham, NC, 27708, USA.
John A GallisDuke Global Health Institute, Duke University, Durham, NC, 27708, USA.
Eric B LaberDuke Global Health Institute, Duke University, Durham, NC, 27708, USA.
Susanna NaggieDepartment of Medicine, School of Medicine, Duke University, Durham, NC, 27708, USA.
Christopher W WoodsDuke Global Health Institute, Duke University, Durham, NC, 27708, USA.
Evan MyersDuke Clinical Research Institute, Duke University, Durham, NC, 27708, USA.
L Gayani Tillekeratne *Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, 80000, Sri Lanka.
Melissa H Watt *Department of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, UT, 84108, USA.

Funding

A randomized controlled trial of a novel, evidence-based algorithm for managing lower respiratory tract infection in a resource-limited settingR01AI168420 · NIAID · DUKE UNIVERSITY · PI GAYANI TILLEKERATNE · 2022 to 2026
$3.4M
NIAID NIH HHS R01 AI168420
6 · The paper itself

Abstract

objectivesLower respiratory tract infections (LRTIs) pose significant diagnostic challenges, especially in low- and middle-income countries (LMICs), where access to diagnostics and clinical tools is limited. This qualitative study explored Sri Lankan physicians’ attitudes and practices regarding current approaches to diagnosing and managing LRTIs in adult patients.

resultsWe interviewed fifteen internal medicine physicians from six public hospitals throughout Sri Lanka. Participants’ management of LRTIs primarily depended on clinical history, basic investigations such as white blood cell count, and clinical judgment and experience. Guidelines (e.g., from the Sri Lankan College of Microbiologists and British Thoracic Society) were consulted, but physicians reported deviations when faced with drug unavailability or severe LRTI cases. Use of rapid pathogen-based diagnostics was limited given resource constraints. The biomarker test C-reactive protein (CRP) was used commonly, while the biomarker test procalcitonin (PCT) was used rarely due to high cost and limited access. Physicians frequently used clinical decision support tools (CDSTs), including CURB-65 and the Pneumonia Severity Index (PSI), on their mobile phones for determining severity of LRTI. Overall, physicians relied on a combination of clinical judgment and CDSTs, with selective use of guidelines and rapid diagnostics, in managing LRTIs. These results can help inform the development of strategies for improving the diagnosis and management of LRTIs in Sri Lanka.

Indexed as

Attitude of Health PersonnelPhysiciansPractice Patterns, Physicians'Respiratory Tract InfectionsAdultBiomarkersC-Reactive ProteinFemaleHumansMaleProcalcitoninResource-Limited SettingsSri LankaBiomarkersC-Reactive ProteinProcalcitoninDiagnosticsElectronic clinical decision support toolsGuidelinesLower respiratory tract infectionsSri lanka

Identifiers

PMID41723542
PMCPMC13032363

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.