ReviewBMC infectious diseases2026
Multidrug-resistant Eikenella corrodens causing maxillary osteomyelitis with sequestrum and oronasal fistula: a rare case and literature review.
Review in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEikenella corrodens is a commensal organism of the oral and upper respiratory tract and is only rarely implicated in osteomyelitis. Maxillary involvement is considered uncommon, likely reflecting the rich vascularity of the maxilla. To our knowledge, maxillary osteomyelitis complicated by sequestrum and an oronasal fistula caused by multidrug-resistant (MDR) E. corrodens has not been previously reported. CASE PRESENTATION: A 73-year-old man underwent extraction of a mobile maxillary tooth. One month later, he developed recurrent swelling at the extraction site, followed by purulent drainage from a gingival sinus tract and purulent discharge from the right nasal cavity. He received multiple empirical antibiotic courses without sustained improvement. Cone-beam CT revealed destructive changes of the anterior maxilla with sequestrum formation and communication with the nasal cavity. Biopsy excluded malignancy. Culture of purulent material yielded MDR E. corrodens (non-susceptible to at least one agent in ≥ 3 antimicrobial classes), susceptible to carbapenems, with intermediate activity of third-generation cephalosporins. Limited sequestrectomy combined with targeted antibiotic therapy resulted in complete recovery.
conclusionsThis case highlights an unusual presentation of MDR E. corrodens–associated maxillary osteomyelitis with sequestrum and an oronasal fistula. It emphasizes the value of timely imaging and biopsy in persistent post-extraction infections and underscores the potential consequences of repeated empirical antibiotic use in dental practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.