Evidence map›Paper›PMID 41723326›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Implementing a national clinical trial navigator program: a qualitative CFIR analysis of barriers and facilitators from the perspective of people with lived cancer experience.

Nasong Anthony Luginaah, Salah Alhajsaleh, Gregory Anagnostopoulos, Milica Paunic, Dana Inglis, Emmanuel Boujeke, Depen Sharma, Renee Nassar, Olla Hilal, Ibrahim Mohamed and 16 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Nasong Anthony LuginaahSchulich School of Medicine and Dentistry, Western University, London, Canada.
Salah AlhajsalehUniversity of Windsor, Windsor, Canada.
Gregory AnagnostopoulosSchulich School of Medicine and Dentistry, Western University, London, Canada.
Milica PaunicTemerty Faculty of Medicine, University of Toronto, Toronto, Canada.
Dana InglisMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Emmanuel BoujekeSchulich School of Medicine and Dentistry, Western University, London, Canada.
Depen SharmaFaculty of Medicine, University of Ottawa, Ottawa, Canada.
Renee NassarWindsor Regional Hospital, Windsor, Canada.
Olla HilalDepartment of Epidemiology, Western University, London, Canada.
Ibrahim MohamedSchulich School of Medicine and Dentistry, Western University, London, Canada.
Pratham GuptaSchulich School of Medicine and Dentistry, Western University, London, Canada.
Christina TrieuUniversity of Windsor, Windsor, Canada.
Ria PatelSchulich School of Medicine and Dentistry, Western University, London, Canada.
Michael ToumaWindsor Regional Hospital, Windsor, Canada.
Govana SadikWindsor Regional Hospital, Windsor, Canada.
Anaam JaetUniversity of Windsor, Windsor, Canada.
Swati KaliaWindsor Regional Hospital, Windsor, Canada.
Ali Abdel RaheemSchulich School of Medicine and Dentistry, Western University, London, Canada.
Rhonda Abdel-NabiSchulich School of Medicine and Dentistry, Western University, London, Canada.
Laurice ArayanDepartment of Oncology, Windsor Regional Hospital, Windsor, Canada.
Laith AlmasriTemerty Faculty of Medicine, University of Toronto, Toronto, Canada.
Nicole Zhongyue ShenMax Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Leonard YooRady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
Lee McGrathWindsor Regional Hospital, Windsor, Canada.
Caroline HammDepartment of Oncology, Windsor Regional Hospital, Windsor, Canada.
Megan DelisleDepartment of Surgery, University of Manitoba, Winnipeg, Canada. Megan.Delisle@umanitoba.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Clinical Trials Navigator (CTN) Program is a pan-Canadian navigation service designed to improve access to cancer clinical trials. Despite promising early results, the program has not been widely implemented. This study examines the perceived barriers and facilitators to implementation from the perspective of individuals with lived cancer experience.

methodsUsing an adapted Consolidated Framework for Implementation Research (CFIR) interview guide, we conducted 60-min semistructured interviews with 20 people with lived cancer experiences. Data were analyzed using both inductive and deductive coding across the five CFIR domains.

resultsParticipants identified several facilitators to implementation. Participants expressed strong altruism and a willingness to participate in clinical trials. They felt the program addressed a critical gap in clinical trial access. The program's centralized, no-cost, and Canada-specific design enhanced its perceived accessibility and trustworthiness. The integration of culturally aligned navigators facilitated effective communication and trust among diverse populations. Key barriers included limited awareness of the CTN Program among the patients and clinicians, as well as financial and logistical challenges to accessing clinical trials. Communication from clinicians about trial opportunities was often inconsistent, leaving many patients unaware of their options unless they actively searched for themselves.

conclusionPeople with lived cancer experience in our study identified the CTN Program as a unique intervention with the potential to improve equitable access to cancer clinical trials in Canada. However, successful scale-up will require coordinated efforts to raise awareness, strengthen clinician engagement, and alleviate financial and logistical burdens associated with participating in clinical trials.

Indexed as

Clinical Trials as TopicHealth Services AccessibilityNeoplasmsPatient NavigationAdultAgedAltruismCanadaFemaleHumansInterviews as TopicMaleMiddle AgedQualitative ResearchTrustCancerClinical trialsPatient navigation

Identifiers

PMID41723326

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.