Evidence map›Paper›PMID 41723283›Full record

ArticleLangenbeck's archives of surgery2026

Longitudinal analysis of body compositions following Roux-en-Y gastric bypass.

Zubaidah Nor Hanipah, Gabriela de O Lemos, Sophia Ramirez, Venkata Satya Naga Arun Kousik Dhulipala, Karteek Popuri, Mirza Faisal Beg, Shengping Yang, Philip R Schauer, Vance L Albaugh, Steven B Heymsfield

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Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zubaidah Nor HanipahMetamor Institute, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Rd., Baton Rouge, LA, 70808, USA.ORCID http://orcid.org/0000-0003-1184-6987
Gabriela de O LemosMetabolism-Body Composition Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA.
Sophia RamirezMetabolism-Body Composition Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA.
Venkata Satya Naga Arun Kousik DhulipalaDepartment of Computer Science, Memorial University of Newfoundland, St. John's, NL, Canada.
Karteek PopuriDepartment of Computer Science, Memorial University of Newfoundland, St. John's, NL, Canada.
Mirza Faisal BegSchool of Engineering Science, Simon Fraser University, Vancouver, BC, Canada.
Shengping YangBiostatistics Department, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA.
Philip R SchauerMetamor Institute, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Rd., Baton Rouge, LA, 70808, USA.
Vance L AlbaughMetamor Institute, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Rd., Baton Rouge, LA, 70808, USA.
Steven B HeymsfieldMetabolism-Body Composition Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA. Steven.heymsfield@pbrc.edu.

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

backgroundRoux-en-Y gastric bypass (RYGB) is associated with substantial weight loss and improved obesity-related comorbidities. However, outcomes on body composition, particularly skeletal muscle (SM), visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT) remain inconsistent due to limitations in measurement techniques.

objectiveEvaluate longitudinal changes in SM, VAT, and SAT volumes (cm3) following RYGB using Data Analysis Facilitation Suite (DAFS), an automated computed tomography (CT) analysis software.

methodsIn this prospective pilot study, nine female patients underwent low-dose abdominal and pelvic CT imaging at baseline, 3-, and 6-months post-RYGB. Volumetric analysis from the ninth thoracic veterbra (T9) to the sacrum was performed using DAFS. Changes in SM, VAT, and SAT were assessed using paired t-tests.

resultsParticipants (mean ± SD; age 35 ± 9 years, BMI 48 ± 10 kg/m²) experienced substantial weight loss (14 ± 5% at 3 months, 25 ± 7% at 6 months; p < 0.001). SAT and VAT volumes decreased significantly by 21% and 27% at 3 months, and by 31% and 47% at 6 months, respectively (all p < 0.001). In contrast, SM volume showed a significant decline of 14% at month 3 (p < 0.001) and then plateaued thereafter.

conclusionThe changes over time differ substantially among SM, VAT and SAT after Roux-en-Y gastric bypass, reflecting the distinct physiological responses and metabolic improvement of different tissue types. Larger and longer clinical studies are needed to validate these findings.

Indexed as

Body CompositionGastric BypassObesity, MorbidAdultFemaleHumansIntra-Abdominal FatLongitudinal StudiesMiddle AgedMuscle, SkeletalPilot ProjectsProspective StudiesSubcutaneous FatTomography, X-Ray ComputedTreatment OutcomeWeight LossComputed tomographyRoux-en-Y gastric bypassSkeletal muscleSubcutaneous adipose tissueVisceral adipose tissue

Identifiers

PMID41723283
PMCPMC12929320

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.