Evidence map›Paper›PMID 41723158›Full record

ArticleNature communications2026

RORγt

Jie Zhao, Jiacheng Hao, Jincheng Chen, Mengze Lyu, Haoyu Liu, Na Li, Panwei Song, Wenyan Wang, Coco Chu, Gregory F Sonnenberg and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jie Zhao *Institute for Immunology, Tsinghua University, Beijing, China.ORCID http://orcid.org/0009-0000-6039-5866
Jiacheng Hao *Institute for Immunology, Tsinghua University, Beijing, China.ORCID http://orcid.org/0000-0003-4025-7241
Jincheng Chen *Institute for Immunology, Tsinghua University, Beijing, China.
Mengze LyuJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID http://orcid.org/0000-0002-8509-7969
Haoyu LiuInstitute for Immunology, Tsinghua University, Beijing, China.
Na LiInstitute for Immunology, Tsinghua University, Beijing, China.
Panwei SongInstitute for Immunology, Tsinghua University, Beijing, China.
Wenyan WangInstitute for Immunology, Tsinghua University, Beijing, China.ORCID http://orcid.org/0000-0001-7663-9124
Coco ChuInstitute for Immunology, Tsinghua University, Beijing, China.
Gregory F SonnenbergJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID http://orcid.org/0000-0003-0948-5908
Xiaohuan GuoInstitute for Immunology, Tsinghua University, Beijing, China. guoxiaohuan@tsinghua.edu.cn.ORCID http://orcid.org/0000-0001-5152-3010

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32530036, 32170872, 82122030 and 31821003Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) Z210015
6 · The paper itself

Abstract

Oral tolerance represents a hallmark of intestinal mucosal immunity to prevent inflammatory responses to harmless natural antigens, such as dietary components or commensal organisms. According to recent studies, RORγt

Indexed as

Antigen-Presenting CellsAntigensImmune ToleranceNuclear Receptor Subfamily 1, Group F, Member 3AnimalsCore Binding Factor Alpha 3 SubunitDendritic CellsFemaleIntestinal MucosaMiceMice, Inbred C57BLMice, KnockoutT-Lymphocytes, RegulatoryAntigensCore Binding Factor Alpha 3 SubunitNuclear Receptor Subfamily 1, Group F, Member 3Rorc protein, mouse

Identifiers

PMID41723158
PMCPMC13036028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.