Evidence map›Paper›PMID 41723141›Full record

ArticleBDJ open2026

A two year randomized clinical trial comparing opposing enamel wear from milled resin-matrix ceramic and direct bulk-fill composite overlays.

Esraa Esmeail H Elhaddad, Aly Ayman M Elkady, Dina Fayez S Diab

Registry-linked trialAbstract read
In one paragraph

Article in BDJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06807125 (Intraoral Wear Measurement of Opposing Enamel to Indirect Milled Resin Matrix Ceramic Versus Direct Bulk Fill Resin Composite in Posterior Teeth After Using 2 Years), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06807125 nacompletednot on this map

Intraoral Wear Measurement of Opposing Enamel to Indirect Milled Resin Matrix Ceramic Versus Direct Bulk Fill Resin Composite in Posterior Teeth After Using 2 Years: Randomized Clinical Trial

TypeinterventionalSponsorMisr University for Science and TechnologyRan2023 to 2025Enrolled26ConditionsDental WearArmsResin matrix ceramic block
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Esraa Esmeail H ElhaddadConservative Dentistry Department, Faculty of Dentistry, Misr University for Science and Technology, Cairo, Egypt. asraa.esmail@must.edu.eg.
Aly Ayman M ElkadyFixed Prosthodontics Department, Faculty of Dentistry, Misr International University, Cairo, Egypt.
Dina Fayez S DiabConservative Dentistry Department, Faculty of Dentistry, Egyptian Russian University, Cairo, Egypt.ORCID http://orcid.org/0009-0008-5268-4156

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTooth wear has become an increasingly prevalent clinical issue. It can lead to a reduction in the vertical dimension of occlusion (VDO), heightened tooth sensitivity, and alterations in both function and esthetics due to the progressive loss of dental hard tissues. As the incidence and severity of this multifactorial condition continue to rise, there is a growing need for dentists to adopt minimally invasive approaches for diagnosis, monitoring, and management. This clinical trial was designed to evaluate the amount of enamel wear on opposing enamel in response to either indirect milled resin matrix ceramic or direct bulk-fill resin composite overlays, using intraoral digital scanning technology.

methodsEleven patients in each group received treatment for a total of 22 restorations. Participants were split into two groups, with R1 representing endodontically treated teeth restored with milled resin matrix ceramic overlays and R2 representing endodontically treated teeth restored with direct bulk-fill composite overlays. Using intraoral scanners and three-dimensional surface-based superimposition software, tooth enamel wear was assessed intraorally at baseline (T0), 12 months (T12), and 24 months (T24). The statistical analyses conducted included the Shapiro-Wilk test and the Mann-Whitney U test. The significance level was set at p < 0.05 across all tests.

resultsThe mean linear wear ( ± SD) for the indirect restorations was 0.41 ± 0.27 mm, compared to 0.20 ± 0.05 mm for the direct restorations; this difference was not statistically significant (p = 0.066). Similarly, the mean volumetric wear was 0.13 ± 0.06 mm³ for the indirect group and 0.12 ± 0.08 mm³ for the direct group, with no significant difference between them (p = 1).

conclusionsWithin the limitations of this 2-year clinical evaluation, both direct bulk-fill resin composites and milled resin matrix ceramic overlays demonstrated comparable behavior with opposing enamel in posterior teeth, with no statistically significant differences between the tested materials.

trial registrationThe study was registered at ClinicalTrials.gov on 29 Jan 2025 (#NCT06807125).

Identifiers

PMID41723141
PMCPMC12924777

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.