Research note: An Adaptive Lasso-based genome-wide association study of blood and meat spots in chicken eggs.

Xiaolong Ma, Xing Chen, Xue Cheng, Wei Liu, Zhonghua Ning

Abstract read

In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaolong MaNational Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Xing ChenNational Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Xue ChengNational Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Wei LiuHebei Zhongnongmufeng Layer Breeding Co., Ltd., Zhuozhou 072750, China.

Zhonghua NingNational Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. Electronic address: ningzhh@cau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood and meat spots (BMS) are common internal defects in chicken eggs that compromise egg quality. To reveal genes contribute to BMS formation, we performed an Adaptive Lasso-based genome-wide association study (ALGWAS) of Rhode Island Red (RIR) hens. The results showed that the heritability of BMS was 0.13. Based on ALGWAS, we identified one significant and 144 suggestive SNPs associated with BMS. Within the significant locus, eight candidate genes were annotated (TNFRSF1A, CECR1, TRIM45, CALD1, SIDT1, VTCN1, USF3, ATP6V1A). Among these, VTCN1 emerged as the strongest candidate, supported by eQTL annotation and its established function as an immune checkpoint regulator that modulates inflammation, vascular integrity, and T-cell responses.

Indexed as

ChickensEggsGenome-Wide Association StudyAnimalsFemalePolymorphism, Single NucleotideAdaptive Lasso based genome-wide association studyBlood and meat spotsChicken eggEgg quality

Identifiers

PMID41722230

DOI10.1016/j.psj.2026.106639

PMCPMC12934296

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.