Evidence map›Paper›PMID 41722046›Full record

ArticleCell reports2026

Lateral hypothalamus directs stress-induced modulation of acute and psoriatic itch.

Jagat Narayan Prajapati, Aynal Hoque, Manojeet Pattanayak, Giriraj Sahu, Arnab Barik

Abstract read
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In one paragraph

Article in Cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jagat Narayan PrajapatiCentre for Neuroscience, Indian Institute of Science, Bengaluru, Karnataka 560012, India.
Aynal HoqueMolecular Biophysics Unit, Indian Institute of Science, Bengaluru, Karnataka 560012, India.
Manojeet PattanayakCentre for Neuroscience, Indian Institute of Science, Bengaluru, Karnataka 560012, India.
Giriraj SahuMolecular Biophysics Unit, Indian Institute of Science, Bengaluru, Karnataka 560012, India.
Arnab BarikCentre for Neuroscience, Indian Institute of Science, Bengaluru, Karnataka 560012, India; Centre for High Impact Neuroscience and Translational Applications (CHINTA), TCG CREST, Kolkata, India. Electronic address: arnabbarik@iisc.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress modulates itch, with acute stress suppressing and chronic stress exacerbating pruritus, yet the underlying neural mechanisms remain unclear. In this study, we investigate the role of lateral hypothalamic area (LHA) neurons in stress-induced itch modulation. Using neural-activity-dependent genetic labeling and chemogenetic tools, we selectively engaged a stress-sensitive population of LHA neurons (LHA

Indexed as

Hypothalamic Area, LateralPruritusPsoriasisStress, PhysiologicalStress, PsychologicalAcute DiseaseAnimalsBrain StemMaleMiceMice, Inbred C57BLNeuronsCP: neurosciencehypothalamusitchneural circuitsoptogeneticspsoriasisstress

Identifiers

PMID41722046
PMCPMC7619200

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.