Evidence map›Paper›PMID 41721831›Full record

ArticlePediatric surgery international2026

Anovestibular fistula versus other subtypes in female patients with low-type anorectal malformation: differential patterns in defecation function improvement and associated anomalies at a single institution.

Toshio Harumatsu, Ayaka Nagano, Koshiro Sugita, Yumiko Tabata, Nanako Nishida, Chihiro Kedoin, Yudai Tsuruno, Masakazu Murakami, Keisuke Yano, Shun Onishi and 6 more

Abstract readComparative Study
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Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Toshio HarumatsuDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Ayaka NaganoDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Koshiro SugitaDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Yumiko TabataDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Nanako NishidaDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Chihiro KedoinDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Yudai TsurunoDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Masakazu MurakamiDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Keisuke YanoDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Shun OnishiDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Koji YamadaDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Waka YamadaDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Takafumi KawanoDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Motofumi TorikaiDepartment of Pediatric Surgery, Kagoshima City Hospital, Kagoshima, Japan.
Tatsuru KajiDepartment of Pediatric Surgery, Kurume University School of Medicine, Kurume, Japan.
Satoshi IeiriDepartment of Pediatric Surgery, Research Field in Medicine and Health Sciences, Medical and Dental Sciences Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan. sieiri@m.kufm.kagoshima-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate associated anomalies and the postoperative defecation function in female patients with low-type anorectal malformations (ARMs), focusing on comparing anovestibular fistula (AVF) with other subtypes.

methodsPatient data were collected between 1984 and 2021. Eighty-seven female patients with low-type ARMs were enrolled after excluding one undetermined case. Associated anomalies, operative procedures, and the long-term defecation function were analyzed and compared between the AVF and non-AVF groups.

resultsAVF was the most common subtype (52.9%), followed by anocutaneous fistula (21.8%), covered anal stenosis (11.5%), anovulvar fistula (10.3%), and covered anal complete (3.4%). Upper urinary tract anomalies and VACTERL association were significantly more frequent in AVF (17.4% and 13.0%) than in non-AVF. Specific associations were identified: trisomy 21 with covered anal complete (100%), perineal groove with anocutaneous fistula (10.5%), and MRKH syndrome with AVF (2.2%). Chronologically, non-AVF low-type ARMs achieved "excellent" evacuation scores at 6 years, whereas AVF patients typically achieved this by 9 years. Individual defecation parameters reached full scores by 7 years in all subtypes except AVF, where constipation persisted beyond 11 years.

conclusionThe postoperative defecation function in female patients with low-type ARMs demonstrates differential improvement patterns, with AVF requiring extended management until at least 9 years.

Indexed as

Anorectal MalformationsDefecationRectal FistulaRectovaginal FistulaAbnormalities, MultipleChildChild, PreschoolFemaleHumansInfantRecovery of FunctionRetrospective StudiesAssociated anomalyDefecation functionFemaleLow-type anorectal malformation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.