Evidence map›Paper›PMID 41721816›Full record

ArticleJACC. Case reports2026

Propafenone Overdose Presenting With Brugada Phenocopy, QRS Widening, and Ventricular Fibrillation.

Qianfeng Xiong, Yaowu Xie

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Qianfeng XiongDepartment of Cardiology, Fengcheng People's Hospital, the Affiliated Fengcheng Hospital of Yichun University, Fengcheng, Jiangxi, China.
Yaowu XieDepartment of Cardiology, Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China. Electronic address: 295677552@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrugada phenocopy (BrP) denotes reversible Brugada-type electrocardiogram changes from transient triggers, requiring management distinct from congenital Brugada syndrome. CASE SUMMARY: A 19-year-old man collapsed at home, regained consciousness in transit, and soon after emergency department arrival had recurrent syncope with ventricular fibrillation, which was defibrillated (200 J). The electrocardiogram showed PR interval approximately 200 milliseconds, QRS interval approximately 160 milliseconds, QTc interval approximately 489 milliseconds, lateral J-waves, and coved ST-segment elevation in V DISCUSSION: The triad of diffuse conduction delay, V TAKE-HOME MESSAGES: BrP resolves after correcting reversible triggers. In sodium-channel blocker toxicity with QRS interval widening, early sodium bicarbonate is first-line therapy.

Indexed as

Brugada phenocopypropafenone overdosesodium bicarbonatesodium-channel blockadeventricular fibrillation

Identifiers

PMID41721816
PMCPMC13080836

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.