Evidence map›Paper›PMID 41721643›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2026

It's a Gas: Bioconjugation With Vapor-Phase Reagents.

Yuxuan Ding, Jun Ohata, Zachary T Ball

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuxuan DingDepartment of Chemistry, Rice University, Houston, Texas, USA.
Jun OhataDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina, USA.
Zachary T BallDepartment of Chemistry, Rice University, Houston, Texas, USA.ORCID https://orcid.org/0000-0002-8681-0789

Funding

National Institute of General Medical Sciences of the National Institutes of Health R35GM155051National Science Foundation CHE-2203948Robert A. Welch Foundation Research Grant C-1680
6 · The paper itself

Abstract

Bioconjugation is a large field with many diverse goals, needs, and challenges, that requires a broad toolbox of fundamentally different synthetic approaches. As an emerging class of bioconjugation reagents, gas molecules bring new reactivity and selectivity concepts. Beyond these fundamental questions, gas-phase reagents may have unique advantages, such as access to porous material and structures, and diffusions/penetration differences in reaction in complex tissues or other contexts. This concept article examines vapor-phase reagents, as well as their reactivity and selectivity, for the modification of natural peptides and proteins.

Indexed as

GasesPeptidesProteinsIndicators and ReagentsGasesIndicators and ReagentsPeptidesProteinsbioconjugationbiphasicgas‐phase reagentslate‐stage diversificationpeptides

Identifiers

PMID41721643
PMCPMC13150058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.