Evidence map›Paper›PMID 41721425›Full record

ArticleCritical care (London, England)2026

Effective buffers in intravenous solutions: reconciling the acid-base effects of organic anions.

Micah Liam Arthur Heldeweg, Santje A S Slot, Martin Vancura, Martin Krbec, Francesco Zadek, František Duška, Lorenzo Giosa

Abstract readLetterComment
In one paragraph

Article in Critical care (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Micah Liam Arthur HeldewegDepartment of Anesthesiology, Amsterdam University Medical Centers, Boelelaan 1117, 1081HV, Amsterdam, The Netherlands. m.heldeweg@amsterdamumc.nl.
Santje A S SlotDepartment of Anesthesia and Intensive Care Medicine, The Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.
Martin VancuraDepartment of Anesthesiology, Amsterdam University Medical Centers, Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.
Martin KrbecDepartment of Anesthesia and Intensive Care Medicine, The Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.
Francesco ZadekDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
František DuškaDepartment of Anesthesia and Intensive Care Medicine, The Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.
Lorenzo GiosaDepartment of Anesthesia and Intensive Care Medicine, The Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.

Funding

Agentura Pro Zdravotnický Výzkum České Republiky NW26J-06-00091
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acid–baseBufferCarbon dioxideCrystalloidLactateMetabolicRespiratorySaline

Identifiers

PMID41721425
PMCPMC12924351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.