Evidence map›Paper›PMID 41721373›Full record

ArticleImplementation science communications2026

Characterizing, protocolizing, and scaling up local adjunctive interventions and implementation strategies to enhance the reach of HIV-prevention and mental health/substance use treatments: a study protocol.

Audrey Harkness, Maeleigh Tidd, Susanne Doblecki-Lewis, Jahn Jaramillo, Guillermo Prado, Ruth Soto Malave, Omar Martinez, Nequiel Reyes, Carlos E Rodriguez-Diaz, Souhail Malavé Rivera and 9 more

Erratum issuedAbstract read
In one paragraph

Article in Implementation science communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Audrey HarknessSchool of Nursing and Health Studies, University of Miami, Coral Gables, USA. aharkness@miami.edu.
Maeleigh TiddSchool of Nursing and Health Studies, University of Miami, Coral Gables, USA.
Susanne Doblecki-LewisDivision of Infectious Diseases, University of Miami Miller School of Medicine, Miami, USA.
Jahn JaramilloDepartment of Public Health Sciences, University of Miami, Miami, USA.
Guillermo PradoSchool of Nursing and Health Studies, University of Miami, Coral Gables, USA.
Ruth Soto MalavePuerto Rico Community Network for Clinical Services, Research and Health Advancement, San Juan, USA.
Omar MartinezDepartment of Population Health Sciences, University of Central Florida, Orlando, USA.
Nequiel ReyesDepartment of Public Health Sciences, University of Miami, Miami, USA.
Carlos E Rodriguez-DiazDepartment of Community Health Sciences, Boston University School of Public Health, Boston, USA.
Souhail Malavé RiveraUniversity of Puerto Rico, Medical Sciences Campus - School of Public Health , San Juan, USA.
Steven SafrenDepartment of Psychology, University of Miami, Coral Gables, USA.
Justin D SmithDepartment of Population Health Science, University of Utah, Spencer Fox Eccles School of Medicine, Salt Lake City, USA.
Radhika SundararajanWeill Cornell Medicine, Department of Emergency Medicine, New York, USA.
Nicole AltenbergSchool of Nursing and Health Studies, University of Miami, Coral Gables, USA.
Daniel FeasterDepartment of Public Health Sciences, University of Miami, Miami, USA.
Jorge LimiaSchool of Nursing and Health Studies, University of Miami, Coral Gables, USA.
Rana SaberFeinberg School of Medicine, Research Application Design and Development Core Center, Northwestern University, Chicago, USA.
Eric W SchrimshawDepartment of Population Health Sciences, University of Central Florida, Orlando, USA.
Edda Santiago-RodriguezDepartment of Community Health Sciences, Boston University School of Public Health, Boston, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Victoria Behar-Zusman · 2023 to 2026
$8.9M
Omuyambi: Traditional healer support to improve HIV viral suppression in rural UgandaR01MH132440 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI Radhika Lu Sundararajan · 2023 to 2026
$2.6M
A type 2 hybrid effectiveness-implementation trial of Community Health Workers to improve screening for postpartum diabetes in urban slums of IndiaR01HD112141 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jyoti S Mathad, Radhika Lu Sundararajan · 2023 to 2026
$2.5M
Leveraging a Strategic Alliance to Characterize, Protocolize, and Scale Up Local Implementation Strategies for Improving PrEP and Mental Health/Substance Use Treatment ReachR01MH138237 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Audrey Harkness · 2024 to 2026
$2.3M
Center for Latino Health Research Opportunities-CLaRO - Investigator Development CoreP50MD019468 · NIMHD · UNIVERSITY OF MIAMI CORAL GABLES · PI Mario R De La Rosa, Guillermo Prado · 2024 to 2026
$2.2M
Culturally-focused HIV Advancements through the Next Generation for Equity (CHANGE) Training ProgramT32MH126772 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DALE, SANNISHA K, FEASTER, DANIEL J · 2021 to 2025
$1.1M
Developing and Pilot Testing Peer Ambassador Stories for Increasing HIV-Prevention and Behavioral Health Treatment Uptake among Latino MSMK23MD015690 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI HARKNESS, AUDREY · 2020 to 2025
$1.1M
Improving HIV testing among Children under five in Rural UgandaR21MH135815 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOOFT, ANNEKA M, NANSERA, DENIS · 2024 to 2024
$432k
National Institute of Allergy and Infectious Diseases P30AI042853NIAID NIH HHS P30 AI042853NICHD NIH HHS R01 HD112141NIMHD NIH HHS K23 MD015690NIMHD NIH HHS K23MD015690NIMHD NIH HHS P50 MD019468NIMHD NIH HHS P50MD019468NIMHD NIH HHS R01MH132440NIMH NIH HHS P30 MH133399NIMH NIH HHS P30MH133399NIMH NIH HHS R01 MH132440NIMH NIH HHS R01 MH138237NIMH NIH HHS R01MH138237NIMH NIH HHS R21 MH135815NIMH NIH HHS R21MH135815NIMH NIH HHS T32 MH126772NIMH NIH HHS T32MH126772
6 · The paper itself

Abstract

backgroundLatino men who have sex with men (MSM) in the United States experience significant HIV disparities, exacerbated by mental health and substance use (MH/SU) concerns. Although evidence-based clinical interventions, such as pre-exposure prophylaxis (PrEP) and MH/SU treatment, can prevent HIV and mitigate MH/SU adverse outcomes, their reach to Latino MSM remain suboptimal. This gap underscores the need for adjunctive interventions and implementation strategies that improve PrEP and MH/SU treatment reach. SOMOS Alianza (San Juan, Orlando, Miami Organizational Strategic Alliance) is a research-practice network spanning three Ending the HIV Epidemic (EHE) jurisdictions. HIV organizations in SOMOS Alianza leverage their expertise in serving Latino MSM to develop and use adjunctive interventions and implementation strategies to improve PrEP and MH/SU treatment reach within their communities. These locally developed interventions and strategies could be scaled across other HIV organizations to meet U.S. EHE goals.

methodsIn Aim 1, we will characterize and assess the degree to which existing adjunctive interventions and strategies used by local organizations align with the existing evidence base. We will combine Rapid Assessment Procedure-Informed Clinical Ethnography and "reverse" implementation mapping to evaluate these interventions and strategies. In Aim 2, we will apply user-centered design principles to develop an online Dashboard featuring interventions and strategies identified in Aim 1. Finally, in Aim 3 we will assess the Dashboard's usability and impact at the organizational level across EHE jurisdictions. Using baseline and 12-month follow-up assessments, we will evaluate outcomes quantitatively and qualitatively, and results will be used to refine the Dashboard for public use. DISCUSSION: This study will go beyond traditional research-to-practice models by identifying and scaling up existing adjunctive interventions and implementation strategies, addressing gaps in implementation science and ultimately improving health outcomes for Latino MSM. Expected outcomes include identifying contextually appropriate and feasible approaches to improve PrEP and MH/SU treatment reach to Latino MSM, developing a scalable Dashboard for dissemination, and creating a generalizable model for implementation, and advancing public health goals aligned with EHE priorities.

Indexed as

Adjunctive interventionsHIV disparitiesImplementation strategiesLatino MSMMental healthPrEPSubstance use

Identifiers

PMID41721373
PMCPMC13032651

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.