Evidence map›Paper›PMID 41721323›Full record

ArticleBMC oral health2026

Development and validation of a nomogram for assessing the risk of periodontitis in youth: a cross-sectional study.

Ping Zhang, Degang Sun, Han Wu, Hongyu Wang, Jie Pan, Yingtao Wu

Abstract readValidation Study
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ping ZhangDepartment of Periodontology, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong, China.
Degang SunDepartment of Cariology and Endodontology, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong, China.
Han WuDepartment of Dean's Office, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong, China.
Hongyu WangDepartment of Periodontology, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong, China.
Jie PanDepartment of Periodontology, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong, China.
Yingtao WuDepartment of Periodontology, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong, China. 347107303@qq.com.

Funding

Medical and Health Scientific Research Project of Qingdao 2023-WJZD150Medical and Health Scientific Research Project of Qingdao 2023-WJZD153Qingdao Key Medical and Health Discipline Project 2025-2027Shandong Provincial Key Medical and Health Discipline of Oral Medicine (Qingdao University Affiliated Qingdao Stomatological Hospital) 2025-2027
6 · The paper itself

Abstract

backgroundPeriodontitis is becoming increasingly common in youth. However, a validated model for assessing the risk of periodontitis in youth is lacking. This study aimed to identify independent risk factors and develop a nomogram for assessing periodontitis risk in youth within a clinical setting.

methodsIn this cross-sectional study, we recruited 807 participants aged 10–24 from the Periodontology Department of Qingdao Stomatological Hospital (Qingdao, Shandong, China). Data on 16 potential risk factors were collected. The participants were randomly allocated to the training and validation cohorts in a 7:3 ratio. Independent factors were identified via univariate and multivariate logistic regression analysis, which were then used to develop a nomogram for assessing the risk of periodontitis in youth within this clinical setting. The model’s validation and performance were rigorously evaluated using the area under the curve (AUC), sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), calibration plots, and decision curve analysis (DCA).

resultsMultivariate logistic regression analysis identified age, mouth breathing, impacted teeth, family history, and higher body mass index (BMI) as significant risk factors of periodontitis, while flossing was a protective factor. Accordingly, a nomogram was developed based on these factors as a risk assessing tool for youth in a clinical setting. Both the training and validation cohorts confirmed the nomogram’s strong assessment performance, evidenced by AUC of 0.837 and 0.783, respectively. The model also maintained high sensitivity (91.2% and 86.5%) and NPV (91.5% and 90.8%) across both cohorts. Good calibration was achieved, with Brier scores of 0.162 (95% CI: 0.145–0.179) for the training cohort and 0.177 (95% CI: 0.148–0.207) for the validation cohort. Furthermore, the model’s clinical utility was underscored by the DCA.

conclusionsWe successfully developed and validated the nomogram for assessing the risk of periodontitis in youth within a clinical setting. With its high AUC, this model shows significant potential to support clinical decision-making by identifying high-risk individuals, thereby facilitating targeted evaluation and optimized management in specialist practice.

Indexed as

NomogramsPeriodontitisAdolescentChildChinaCross-Sectional StudiesFemaleHumansMaleRisk AssessmentRisk FactorsYoung AdultNomogramPeriodontitisRisk factorsYouth

Identifiers

PMID41721323
PMCPMC13032324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.