Evidence map›Paper›PMID 41721294›Full record

ArticleBMC oral health2026

What is associated with joint effusion in the temporomandibular joint, disc displacement, or degenerative bone changes? : a radiological study.

Ryota Takaoka, Yuki Senzaki, Masayuki Ono, Hiroaki Shimamoto, Yuka Uchiyama, Atsutoshi Nakatani, Shoichi Ishigaki, Hirofumi Yatani, Masahiro Nishimura

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryota TakaokaDepartment of Regenerative Prosthodontics, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan. takaoka.ryota.dent@osaka-u.ac.jp.
Yuki SenzakiDepartment of Regenerative Prosthodontics, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Masayuki OnoDepartment of Microbiology, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Hiroaki ShimamotoDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yuka UchiyamaDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Atsutoshi NakataniDepartment of Oral and Maxillofacial Radiology, Health Sciences University of Hokkaido, 1757, Tokubetucho, Ishikarigun, Kanazawa, Hokkaido, 061-0212, Japan.
Shoichi IshigakiDepartment of Regenerative Prosthodontics, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Hirofumi YataniDepartment of Regenerative Prosthodontics, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Masahiro NishimuraDepartment of Regenerative Prosthodontics, Graduate School of Dentistry The University of Osaka, 1-8, Yamadaoka, Suita, Osaka, 565-0871, Japan.

Funding

Japan Society for the Promotion of Science #23K09251Japan Society for the Promotion of Science #25K13085
6 · The paper itself

Abstract

purposeWe aimed to investigate associations between joint effusion (JE) and age, sex, disc displacement, and degenerative condylar changes in the temporomandibular joints (TMJ) through multivariate analysis of a large MRI dataset and to determine its clinical significance. MATERIALS AND

methodsThis retrospective study analysed MRI data from 761 outpatients (1,522 TMJs; average age: 45.8 ± 18.2 years; 582 women, 179 men) with temporomandibular disorder symptoms who underwent MRI examination. Degenerative condylar changes were assessed, and JE was classified into five categories: none, trivial, mild, moderate, and severe. Ordinal logistic regression, accounting for mixed effects, identified associations between JE and predictors (age, sex, disc displacement, and degenerative bone changes: concavity, atrophy, erosion, flattening, osteophytes, and subchondral cysts). Two examiners independently evaluated MRI images, resolving discrepancies through forced consensus.

resultsForced consensus was required for 8.5% (129/1,522) of TMJs. JE classifications of none, trivial, mild, moderate, and severe were observed in 45%, 11.8%, 21%, 14.1%, and 7.7% of TMJs, respectively. Ordinal logistic regression revealed significant associations between JE and age, erosion, osteophytes, and concavity. JE occurrence decreased with age, with erosion showing the strongest association. Disc displacement was not significantly associated with JE.

conclusionsWithin the limitations of this study, JE was significantly associated with degenerative condylar changes rather than disc abnormalities, suggesting its potential as an imaging marker of progressive bone changes. Future large-scale longitudinal investigations are essential to confirm the causal pathways between JE and degenerative condylar changes.

Indexed as

Joint DislocationsTemporomandibular Joint DiscTemporomandibular Joint DisordersAdultAgedAge FactorsFemaleHumansMagnetic Resonance ImagingMaleMandibular CondyleMiddle AgedRetrospective StudiesDegenerative bone changeDisc displacementJoint effusion

Identifiers

PMID41721294
PMCPMC12980951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.