Evidence map›Paper›PMID 41721265›Full record

ArticleBMC geriatrics2026

Development and independent external validation of a novel nomogram to predict cognitive frailty in older adult patients with heart failure.

Jian Liu, Shengjia Xu, Zhiwei Wang, Xueqing Song, Zongke Long, Xiaorong Luan

Abstract readValidation Study
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian Liu *School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Shengjia Xu *Shandong University Cheeloo College of Medicine, The First Clinical College, Jinan, Shandong, China.
Zhiwei WangSchool of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Xueqing SongSchool of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Zongke LongSchool of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Xiaorong LuanSchool of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. 199162000814@sdu.edu.cn.

Funding

National Natural Science Foundation of China 72474121
6 · The paper itself

Abstract

objectivesTo develop and independently externally validate a novel, simple, and validated tool to assess the risk of cognitive frailty in older adult patients with heart failure based on these factors.

designA cross-sectional study. DATA SOURCES: A novel nomogram risk prediction model was developed by recruiting older adult patients with heart failure for data collection from October 2022 to August 2023 at a university general hospital in China. Independent external validation of the developed model was performed on patients collected from March 2023 to June 2023 at a university general hospital at the same level.

methodsUnivariate and multivariate logistic regression analyses were performed for variables that may influence the prevalence of cognitive frailty. The fit and predictive performance of the nomogram risk prediction model was evaluated based on the area under the characteristic curve of the subjects and decision curve analysis.

resultsThe overall prevalence of cognitive frailty in older adult patients with heart failure was 44.5%. The results showed that the predictive ability of the model development cohort was 0.807(95%CI = 0.7640.851, P<0.001). And the predictive ability of the validation cohort was 0.770(95%CI = 0.6670.874, P<0.001), indicating that the model has high accuracy.

conclusionsThe results showed satisfactory predictive performance. The use of this tool helps clinical caregivers to quickly and intuitively identify patients at high risk for the development of cognitive frailty on admission, thus providing evidence to support the early development and implementation of personalized strategies.

Indexed as

FrailtyHeart FailureNomogramsAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHumansMaleRisk AssessmentCognitive frailtyHeart failureNomogramOlder adultRisk prediction

Identifiers

PMID41721265
PMCPMC13032201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.