Evidence map›Paper›PMID 41721150›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Advances in screening for obstructive sleep apnea in stroke patients using the APNOEIC score.

Ana Domínguez-Mayoral, Marta Ferrer Galván, David Núñez-Jurado, María Aguilar Andújar, Jesús Sánchez Gómez, Natalia Fouz Rosón, Carmen Gutiérrez Muñoz, Patricia Guerrero Zamora, José María Benítez Moya, Soledad Pérez-Sánchez and 9 more

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ana Domínguez-MayoralNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain. anam.dominguez.mayoral.sspa@juntadeandalucia.es.
Marta Ferrer GalvánSleep Diseases Unit. Pneumology Department, Virgen Macarena University Hospital, Seville, Spain.
David Núñez-JuradoNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
María Aguilar AndújarSleep Diseases Unit. Neurophysiology Department, Virgen Macarena University Hospital, Seville, Spain.
Jesús Sánchez GómezSleep Diseases Unit. Pneumology Department, Virgen Macarena University Hospital, Seville, Spain.
Natalia Fouz RosónSleep Diseases Unit. Pneumology Department, Virgen Macarena University Hospital, Seville, Spain.
Carmen Gutiérrez MuñozSleep Diseases Unit. Neurophysiology Department, Virgen Macarena University Hospital, Seville, Spain.
Patricia Guerrero ZamoraSleep Diseases Unit. Pneumology Department, Virgen Macarena University Hospital, Seville, Spain.
José María Benítez MoyaSleep Diseases Unit. Pneumology Department, Virgen Macarena University Hospital, Seville, Spain.
Soledad Pérez-SánchezNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain. soledad.perez.sanchez@gmail.com.
Eloy Ferrete RuizNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
José Sánchez MiuraNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
Manuela Bautista BrocoNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
María Luz Jiménez HermosínNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
José Moreno PujolNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
Miguel Ángel GameroNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
Ana BarragánNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
Reyes De TorresNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.
Joan MontanerNeurovascular Research Group, Institute de Biomedicine of Seville, IBiS/Virgen, Macarena University Hospital, CSIC/University of Seville, Seville, Spain.

Funding

Instituto de Salud Carlos III CM23/00216
6 · The paper itself

Abstract

introductionObstructive sleep apnea (OSA) is highly prevalent in stroke patients and contributes to poor outcomes, including increased mortality and neurological deficits. This study aimed to develop a practical screening tool for detecting moderate-to-severe OSA in patients following acute ischemic stroke (AIS). MATERIALS AND

methodsThis prospective study enrolled AIS patients and assessed the respiratory event index (REI) within hours of stroke onset using polygraphy. Demographic and clinical data were collected and analyzed across OSA severities. Univariate and multivariate analyses identified predictors of moderate-to-severe OSA, and receiver operating characteristic (ROC) curves evaluated diagnostic accuracy.

resultsDuring the study period, 72 AIS patients were enrolled. Patients with moderate-to-severe OSA present with facial palsy, have an elevated Mallampati score, and experience a lower nocturnal minimum oxygen saturation. The APNOEIC scale, incorporating these parameters, showed superior diagnostic performance with a sensitivity of 97.8% and specificity of 55.5%, compared to traditional tools like STOP-BANG, which had a sensitivity of 93.3% and specificity of 18.5%.

conclusionThe APNOEIC score showed promising performance for identifying stroke patients at risk of moderate-to-severe OSA. Although results are preliminary and require external validation, implementing such a tool in stroke units could facilitate earlier diagnosis and treatment, potentially improving patient outcomes and reducing healthcare burden.

Indexed as

Mass ScreeningSleep Apnea, ObstructiveStrokeAgedFemaleHumansMaleMiddle AgedPolysomnographyProspective StudiesSensitivity and SpecificitySeverity of Illness IndexAPNOEIC scoreIschemic strokeObstructive sleep apnea (OSA)OSA screeningStroke unit

Identifiers

PMID41721150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.