ReviewNature neuroscience2026
Behavioral timescale synaptic plasticity: properties, elements and functions.
Review in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Instructive signals drive learning through behavioral timescale synaptic plasticity in the hippocampus and beyond.Current research in neurobiology · 2026Article
- Striatal endocannabinoids drive one-shot learning.Nature neuroscience · 2026Article
- Irregular and bursty neuronal firing extend spike-timing dependent plasticity window to behavioral timescales.iScience · 2026Article
- Increased CA3 burst activity inbioRxiv : the preprint server for biology · 2026Article
- Learning Shapes the Energy Cost of Neural Tasks.bioRxiv : the preprint server for biology · 2026Article
- Synaptic Plasticity as a Function of the Temporal Derivative.bioRxiv : the preprint server for biology · 2026Article
- Dendritic Inhibition Terminates Plateau Potentials in CA1 Pyramidal Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Cerebellum violates Marr-Albus predictions to train synapses on long-term anticipatory goals.bioRxiv : the preprint server for biology · 2026Article
- New directions for complex systems in contemporary neuroscience: a morphodynamic and emergent function approach.Frontiers in computational neuroscience · 2026Review
- The grand challenge in cellular neurophysiology.Frontiers in cellular neuroscience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Understanding how brains learn and remember remains among the most important challenges in science. Recent studies in the hippocampus implicate a new form of synaptic plasticity, named behavioral timescale synaptic plasticity (BTSP), in the generation of experience-based learning and memory. BTSP is a strong, bidirectional type of plasticity that affects synaptic weights over many seconds of time. It is induced by single dendritic plateau potentials, as opposed to many action potentials, and is thus capable of producing new place cells in one trial. Plateau potential initiation is controlled, at least in part, by local feedback inhibition and an instructive input from a higher-order brain region that potentially links the plasticity to current experience. The new credit assignment procedure in BTSP provides a nonstandard mechanism for memory storage and retrieval that could mitigate the need for widespread synapse stabilization. In addition, it may allow hippocampal networks both to form memories of specific behavioral episodes and to generalize on the basis of past episodes. Finally, recent BTSP investigations could provide a basis for future explorations into how brains learn and remember, ranging from the systems and cognitive levels down to the basic biochemical building blocks of learning and memory.
Indexed as
Identifiers
41720996What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.