ArticleScientific reports2026
Association between castration-induced changes in circadian body temperature rhythms and gut microbiome diversity in goats.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Castration is a routine management practice in livestock production, used to control temperament, reproduction, and carcass traits. Beyond these intended outcomes, castration induces substantial physiological changes, particularly in energy metabolism and thermoregulation. Recent studies have revealed close interactions between host circadian physiology and the gut microbiome, suggesting that disturbances in this relationship may influence animal performance and welfare. However, the effects of castration-induced alterations in circadian body temperature (CBT) rhythms on intestinal microbial composition remain poorly understood in ruminants. This study investigated the association between castration, CBT rhythmicity, and gut microbiota composition in goats. Castration significantly modified CBT rhythms in both early- and late-castrated animals. Linear mixed-effects cosinor analysis demonstrated distinct changes in the amplitude and acrophase of CBT oscillations, with more pronounced effects observed in late-castrated goats. These physiological changes were accompanied by shifts in intestinal microbial β-diversity, as shown by distance-based redundancy analysis, suggesting that castration-induced alterations in host circadian regulation were associated with changes in microbial community structure. Given the small sample size, this study should be considered exploratory and hypothesis-generating. These findings provide new insights into the interplay between host circadian biology and the gut microbiome in ruminants. The present study may inform future research and management approaches aimed at improving animal health and productivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.