Evidence map›Paper›PMID 41719039›Full record

ArticleJAMA network open2026

Decision-Making Approaches Used to Limit Potentially Nonbeneficial Life-Prolonging Interventions.

Jason N Batten, Sofia Weiss Goitiandia, Julia K Axelrod, Helen O Chernicoff, Ariadne A Nichol, Lorraine M Pereira, Jacob A Blythe, Jacqueline M Kruser, Elizabeth W Dzeng

Abstract read
In one paragraph

Article in JAMA network open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jason N BattenDepartment of Anesthesiology and Perioperative Medicine, University of California, Los Angeles, Los Angeles.
Sofia Weiss GoitiandiaDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco, San Francisco.
Julia K AxelrodDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco, San Francisco.
Helen O ChernicoffDepartment of Palliative Medicine, Swedish Cherry Hill, Seattle, Washington.
Ariadne A NicholSchool of Medicine, University of California, San Diego, San Diego.
Lorraine M PereiraHarvard Medical School, Boston, Massachusetts.
Jacob A BlytheHarvard Medical School, Boston, Massachusetts.
Jacqueline M KruserDepartment of Medicine, Division of Allergy, Pulmonary, and Critical Care; University of Wisconsin-Madison, Madison.
Elizabeth W DzengDivision of Hospital Medicine, Department of Medicine, University of California, San Francisco, San Francisco.

Funding

Understanding and Addressing Systemic Factors Influencing the Quality of End-of-Life Care in Older AdultsK76AG074906 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Elizabeth Dzeng · 2022 to 2026
$1.1M
NIA NIH HHS K76 AG074906
6 · The paper itself

Abstract

Importance: Professional society policy statements recommend that clinicians limit (ie, withhold or withdraw) potentially nonbeneficial life-prolonging interventions by (1) achieving a shared decision with patients or surrogates or (2) initiating an institutional process to address disagreement with patients or surrogates. However, in the context of a health care system with a default tendency toward life prolongation, it is unclear whether clinicians rely entirely on these recommended approaches or resort to alternate approaches. Objective: To characterize the range of decision-making approaches clinicians report using to limit potentially nonbeneficial life-prolonging interventions. Design, Setting, and Participants: This qualitative study was conducted at 3 tertiary academic medical centers in Washington and California. Clinicians were sampled from emergency department, medical ward, medical intensive care unit, geriatrics, and palliative care services between February 2018 and June 2022 for in-depth, semistructured interviews. Results were analyzed between August 2023 and May 2025. Main Outcomes and Measures: After qualitatively analyzing interviews to identify decision-making approaches, we developed a framework of approaches that categorized each as a recommended or alternate approach. Results: We conducted 101 interviews (53 attending physicians [52%], 16 trainee physicians [16%], 6 advanced practice clinicians [6%], 21 nurses [21%], 3 chaplains [3%], and 2 social workers [2%]; 59 women [58%], 42 men [42%]; mean age, 42 years [range, 27-74 years]; mean years of experience, 14 [range, 1-52]). We identified 6 decision-making approaches: (1) providing an informed choice regarding interventions, (2) making a recommendation to limit interventions, (3) stating a plan to limit interventions, (4) explicitly not offering interventions, and (5) not mentioning interventions. In rare cases of intractable conflict, clinicians reported using an option of last resort: (6) invoking an institutional process to limit interventions. Respondents reported challenges with limiting interventions via the recommended approaches of shared decision-making (approaches 1-3) and institutional processes (approach 6), which sometimes discouraged the use of these approaches. While respondents recounted successfully using alternate approaches (approaches 3-5), they described interclinician and interhospital practice variation, as well as ethical and practical uncertainties. Conclusions and Relevance: In this qualitative study, clinicians reported substantial challenges using recommended approaches to limit potentially nonbeneficial life-prolonging interventions. Some clinicians reported using alternate approaches that are not supported in professional society policy statements.

Indexed as

Clinical Decision-MakingDecision MakingLife Support CareWithholding TreatmentAdultCaliforniaFemaleHumansMaleMiddle AgedQualitative ResearchWashington

Identifiers

PMID41719039
PMCPMC12924098

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.