ReviewApoptosis : an international journal on programmed cell death2026
Apoptotic extracellular vesicles: unveiling mechanisms, diverse functions, and biomedical implications.
Review in Apoptosis : an international journal on programmed cell death, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Apoptotic extracellular vesicles (ApoEVs), once dismissed as inert "cellular debris," are now recognized as dynamic membrane-bound vesicles actively released during apoptosis, functioning as essential signaling platforms that coordinate tissue homeostasis and disease progression. Research reveals that through unique molecular signatures and surface properties, ApoEVs drive apoptotic corpse clearance, modulate immune responses, and mediate intercellular crosstalk, thereby exerting multifaceted influences on tissue repair and disease pathogenesis. This review systematically outlines the biogenesis, molecular regulators, and key characteristics of ApoEVs. We focus on their pivotal roles in both physiological homeostasis and disease states, highlighting their substantial translational potential for treating diverse conditions, including immune disorders, osteoporosis, skin injury, and cancer. Finally, we provide a forward-looking perspective on key challenges and translational opportunities, aiming to bridge fundamental insights into ApoEV biology with their clinical application in disease therapy.
Indexed as
Identifiers
41718812What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.