Evidence map›Paper›PMID 41718484›Full record

ArticleAntimicrobial agents and chemotherapy2026

Pharmacokinetic-pharmacodynamic modeling to evaluate the relative impact of immune response and meropenem on bacterial killing

Raphaël Saporta, Natália Tassi, Veronica Biordi, Olga Ticha, Aghavni Ginosyan, Irena Loryan, Elisabet I Nielsen, Isabelle Bekeredjian-Ding, Bernhard Kerscher, Lena E Friberg

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Raphaël SaportaDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.ORCID 0009-0005-3459-6839
Natália TassiDivision of Infectious Diseases, Paul-Ehrlich-Institut, Langen, Germany.
Veronica BiordiDivision of Infectious Diseases, Paul-Ehrlich-Institut, Langen, Germany.
Olga TichaDivision of Infectious Diseases, Paul-Ehrlich-Institut, Langen, Germany.
Aghavni GinosyanDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.ORCID 0009-0005-5546-6099
Irena LoryanDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-1557-4416
Elisabet I NielsenDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-0725-214X
Isabelle Bekeredjian-DingDivision of Infectious Diseases, Paul-Ehrlich-Institut, Langen, Germany.ORCID 0000-0001-6646-5888
Bernhard KerscherDivision of Infectious Diseases, Paul-Ehrlich-Institut, Langen, Germany.ORCID 0000-0001-9300-7401
Lena E FribergDepartment of Pharmacy, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-2979-679X

Funding

H2020 Marie Skłodowska-Curie Actions 861323Swedish Research Council 2022-00657
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsMeropenemAnimalsDose-Response Relationship, DrugFemaleLungMiceMicrobial Sensitivity TestsNeutropeniaAnti-Bacterial AgentsMeropenemimmune responsemeropenemmodelingpharmacokinetics-pharmacodynamics

Identifiers

PMID41718484
PMCPMC13041408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.