Evidence map›Paper›PMID 41718271›Full record

ReviewJournal of xenobiotics2026

Genetic Modulation of Mercury Exposure on Perinatal and Birth Outcomes: A Systematic Review and Meta-Analysis of Gene-Environment Interactions.

Aqsa Aufa Syauqi Sadana, Saekhol Bakri, Shinji Tokonami, Eka Djatnika Nugraha, Hasnawati Amqam, Muflihatul Muniroh

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of xenobiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aqsa Aufa Syauqi SadanaMaster's Program in Biomedical Science, Faculty of Medicine, Universitas Diponegoro, Semarang 50275, Indonesia.ORCID 0009-0005-2212-0403
Saekhol BakriDepartment of Public Health Science, Faculty of Medicine, Universitas Diponegoro, Semarang 50275, Indonesia.
Shinji TokonamiInstitute of Radiation Emergency Medicine, Hirosaki University, Hirosaki-shi 036-8560, Japan.ORCID 0000-0002-6617-7402
Eka Djatnika NugrahaResearch Center of Nuclear Safety, Metrology and Quality Technology, Research Organization of Nuclear Technology (ORTN), National Research and Innovation Agency (BRIN), South Tangerang 15314, Indonesia.ORCID 0000-0002-6989-2313
Hasnawati AmqamDepartment of Environmental Health, Faculty of Public Health, Hasanuddin University, Makassar 90245, Indonesia.ORCID 0000-0003-4961-8517
Muflihatul MunirohCenter of Clinical Toxicology and Environmental Health (CCTEH), Faculty of Medicine, Universitas Diponegoro, Semarang 50275, Indonesia.ORCID 0000-0003-0020-6722

Funding

Indonesian Collaboration Research Grant, Institute for Research and Community Service 325-22/UN7.D2/PP/V/2025
6 · The paper itself

Abstract

Genetic polymorphisms can modulate susceptibility to mercury (Hg) toxicity by altering metabolic and detoxification pathways. This review evaluated the association between genetic variants, Hg exposure, and obstetric outcomes. A systematic search of Scopus, PubMed and ScienceDirect through May 2025 identified 12 eligible studies (

Indexed as

genetic polymorphismGSTP1mercuryperinatalpregnancy outcomes

Identifiers

PMID41718271
PMCPMC12921806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.