Evidence map›Paper›PMID 41718243›Full record

ArticleEuropean burn journal2026

Oxygen-Enriched Olive-Oil Dressing in Moderate-Degree Pediatric Burns: Impact on Care and Budget over a 4-Year Period in a Tertiary Children's Hospital.

Silvia Borghetti, Ugo Maria Pierucci, Chiara Palladino, Stefania Vimercati, Francesca Selmin, Andrea Marcellusi, Giulia Tosi, Alessia Musitelli, Elena Zoia, Irene Paraboschi and 1 more

Abstract read
In one paragraph

Article in European burn journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Silvia BorghettiPharmacy Unit, ASST Fatebenefratelli-Sacco, 20131 Milan, Italy.
Ugo Maria PierucciDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0001-7370-5122
Chiara PalladinoPharmacy Unit, ASST Fatebenefratelli-Sacco, 20131 Milan, Italy.
Stefania VimercatiPharmacy Unit, ASST Fatebenefratelli-Sacco, 20131 Milan, Italy.
Francesca SelminDepartment of Pharmaceutical Science (DISFARM), University of Milan, 20122 Milan, Italy.ORCID 0000-0002-3680-6124
Andrea MarcellusiDepartment of Pharmaceutical Science (DISFARM), University of Milan, 20122 Milan, Italy.ORCID 0000-0002-3974-3798
Giulia TosiPharmacy Unit, ASST Fatebenefratelli-Sacco, 20131 Milan, Italy.
Alessia MusitelliDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.
Elena ZoiaAnesthesia and Intensive Care Unit, Vittore Buzzi Children's Hospital, 20154 Milan, Italy.
Irene ParaboschiDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.
Gloria PelizzoDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, 20154 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric burns cause considerable morbidity and hospital resource use. Advanced dressings on moderate-degree pediatric burns that accelerate healing may offset acquisition costs by shortening length of stay (LOS).

objectiveThe aim of this study was to assess the budget impact of introducing an oxygen-enriched olive-oil dressing for pediatric burns (grade I-IIG; total body surface area < 20%) at a tertiary children's hospital.

methodsA hospital-perspective budget impact analysis was conducted according to ISPOR guidance over a 4-year horizon (2022-2025). The study population included 32 inpatients (<18 years) with non-extensive, moderate-degree burns treated between 2022 and 2023. Two scenarios were modeled: (i) standard of care (SoC) and (ii) SoC plus the oxygen-enriched olive-oil dressing (OEoD), with annual caseload projections to 2025. Costs combined treatment (dressings, drugs, and devices) and hospitalization data provided by the hospital's Control & Management Unit. The average daily hospitalization cost was €1438.99.

resultsCompared with SoC, the OEoD scenario increased per-patient dressing costs (mean €271.4 vs. €121.9) but reduced LOS (mean 7.3 vs. 16.6 days), leading to lower overall hospitalization expenditure. Total annual costs decreased by 7%, 13%, 16%, and 18% across 2022-2025, respectively (for example, 2025: €612,516 vs. €751,445; Δ -€138,929). Cumulative 4-year savings reached €337,399. Deterministic sensitivity analysis confirmed the robustness of these findings, with savings persisting under variable assumptions.

conclusionsDespite higher acquisition costs, oxygen-enriched olive-oil dressings were associated with shorter LOS and meaningful budget savings in pediatric burn care. These results support their integration into multidisciplinary burn management pathways and call for further prospective multicenter validation.

Indexed as

advanced wound dressingbudget impact analysishospital costsoxygen-enriched olive-oil dressingpediatric burns

Identifiers

PMID41718243
PMCPMC12922114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.