Evidence map›Paper›PMID 41718066›Full record

SynthesisAdvances in respiratory medicine2026

Evaluating the Impact of Inspiratory Muscle Training on Respiratory Function and Exercise Capacity in Pulmonary Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Saja Alrashedi, Lama Alharbi, Meshal Alotaibi, Inad Alzahrani, Albara Jad, Qamar Aldoboke, Suroor Algethami, Raghda Alrabah, Rana Alharbi, Ali Al Nuwaiser and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Advances in respiratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saja AlrashediDepartment of Physical Therapy and Health Rehabilitation, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0009-0009-2401-8364
Lama AlharbiDepartment of Medicine and Surgery, College of Medicine, Qassim University, Qassim 52571, Saudi Arabia.
Meshal AlotaibiDepartment of Medicine and Surgery, College of Medicine, Umm Al-Qura University, Makkah 24268, Saudi Arabia.ORCID 0009-0001-7255-7815
Inad AlzahraniDepartment of Medicine and Surgery, College of Medicine, Umm Al-Qura University, Makkah 24268, Saudi Arabia.ORCID 0009-0004-0868-8572
Albara JadDepartment of Medicine and Surgery, College of Medicine, Umm Al-Qura University, Makkah 24268, Saudi Arabia.
Qamar AldobokeCollege of medicine, King Saud bin Abdulaziz University, Jeddah 22384, Saudi Arabia.
Suroor AlgethamiDepartment of Medicine and Surgery, College of Medicine, Umm Al-Qura University, Makkah 24268, Saudi Arabia.
Raghda AlrabahDepartment of Medicine and Surgery, College of Medicine, Qassim University, Qassim 52571, Saudi Arabia.
Rana AlharbiDepartment of Medicine and Surgery, College of Medicine, Qassim University, Qassim 52571, Saudi Arabia.
Ali Al NuwaiserDepartment of Medicine and Surgery, College of Medicine, Qassim University, Qassim 52571, Saudi Arabia.
Mohammed Al-HaririDepartment of Physiology, Collage of Medicine, Imam Abdulrahman bin Faisal University, Dammam 31441, Saudi Arabia.ORCID 0000-0002-9807-4870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Pulmonary hypertension (PH) is characterized by respiratory muscle weakness, limited exercise tolerance, and reduced quality of life, but inspiratory muscle training (IMT) has emerged as a potential non-pharmacological strategy to improve functional outcomes in this population. This systematic review and meta-analysis evaluated the effects of isolated IMT on respiratory function, exercise capacity, symptom burden, and safety in adults with PH. (2) Methods: A systematic search was conducted in accordance with PRISMA guidelines. Randomized controlled trials involving adults with PH who underwent isolated IMT were included, and respiratory muscle strength, spirometric parameters, exercise capacity, dyspnea, fatigue, quality of life, and adverse events were the outcomes that were assessed. Data were pooled using meta-analytic techniques where appropriate. (3) Results: A total of 130 participants, assigned to five randomized controlled trials, met the inclusion criteria. IMT significantly improved maximal inspiratory pressure (MD = +24.01 cmH

Indexed as

Breathing ExercisesExercise ToleranceHypertension, PulmonaryRespiratory MusclesHumansMuscle StrengthQuality of LifeRandomized Controlled Trials as Topicexercise capacityinspiratory muscle trainingpulmonary hypertensionrespiratory muscle strength

Identifiers

PMID41718066
PMCPMC12921770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.